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Table 2 HDL antioxidant enzyme activities and inflammatory markers

From: High-density lipopoprotein antioxidant capacity, subpopulation distribution and paraoxonase-1 activity in patients with systemic lupus erythematosus

Characteristics SLE patients (n = 51) Controls (n = 49) P Value
PON1 paraoxonase activity (U/l) 118.01 ± 85.49 124.68 ± 102.96 0.857
PON1 arylesterase activity (U/l) 125.65 ± 26.87 148.35 ± 39.34 0.001
Paraoxonase activity/HDL 98.48 ± 69.92 76.20 ± 64.34 0.025
Arylesterase activity/HDL 109.05 ± 38.23 93.51 ± 33.30 0.036
Total HDL antioxidant capacity (%) 165.82 ± 58.28 217.71 ± 54.36 <0.001
OxLDL (mg/l) 3.55 ± 4.19 2.63 ± 3.22 0.291
HsCRP (mg/l) 5.02 ± 6.64 1.68 ± 1.88 0.002
ESR (mm/hour) 24.38 ± 17.96 7.90 ± 5.93 <0.001
IL-6 (ng/l) 0.54 (0–3.25) 0 (0–0.17) 0.002
SAA (ug/l) 19017.07 ± 25899.25 2666.05 ± 2301.11 <0.001
MCP-1 (ng/l) 473.24 (342.72-599.16) 309.72 (242.91-353.86) <0.001
SAA/HDL (ug/mmol) 18217.14 ± 29453.17 1692.24 ± 1459.34 <0.001
  1. ESR erythrocyte sedimentation rate; HDL high-density lipoprotein; hsCRP high-sensitivity C-reactive protein; IL-6 interleukin-6; MCP-1 monocyte chemoattractant protein-1; ox-LDL oxidized low-density lipoprotein; PON1 paraoxonase-1; SAA serum amyloid A
  2. Statistically significant differences are marked in bold