Table 3 Association between rs116843064 (T266M) polymorphism, biochemical measurements and clinical features

N

62

40

5

-

32

55

16

-

 Age (years)

66,18(63,02–69,35)

63,54(62,11–65,92)

59,84(55–64,69)

0,06

67,14(64,11–70,18)

65,37(62,38–68,38)

65,62(60,12–71,13)

0,11

 Sex (%men)

47,7

45,2

57,9

0,65

57,1

44,4

62,5

0,62

 Fasting plasma glucose (mmol/L)

10,7(8,43–12,97)

11,56(10,13–12,99)

11,69(10,16–13,23)

0,74

11,31(8,91–13,71)

11,7(10–13,4)

12,53(10,86–14,2)

0,12

 HbA1c (mmol/L)

10,18(8,08–12,27)

10,61(9,37–11,85)

11,01(9,68–12,34)

0,76

10,36(8,09–12,64)

10,73(9,4–12,07)

11,49(9,98–13)

0,76

BMI (kg/m2)

30,91(29,35–32,46)

29,62(28,59–30,64)

29,44(27,62–31,26)

0,27

42,32(40,83–43,80)

39,94(38,78–41,09)

32,03(30,68–33,37)

0,01

Obesity (%)

52,6

47,7

48,1

0,08

81,3

69

46,7

0,02

Metabolic syndrome (%)

26,2

27,3

26,8

0,21

62,5

51,9

41,94

0,01

 SBP (mm/Hg)

149,33(137,59–161,08)

146,22(137,78–154–67)

137,05(121,5–152,6)

0,40

148,69(139,3–158,08)

143,62(134,51–152,74)

143,56(131,21–155;92)

0,16

 DBP(mm/Hg)

82,59(76,56–88,64)

75,15(68,69–81,62)

75,13(69,34–80,94)

0,13

90,42(82,99–97,86)

83,97(77,06–90,9)

90,37(81,87–98,88)

0,17

 Hypertension (%)

59,1

57,1

55,1

0,28

70

75

81,4

0,06

 TC (mmol/L)

4,55(4,21–4,89)

4,87(4,58–5,16)

5,3(4,7–5,9)

0,44

4,71(4,18–5,24)

4,81(4,43–5,2)

4,98(4,59–5,38)

0,36

TG (mmol/L)

1,98(1,4–2,56)

1,75(1,41–2,09)

1,55(1,23–1,86)

0,04

2,53(2,47–3,19)

2,83(1,83–3,84)

3,23(2,53–3,45)

0,01

 HDL-C (mmol/L)

1,3(1,06–1,54)

1,31(1,16–1,45)

1,41(1,28–1,55)

0,49

1,15(0,94–1,36)

1,19(0,99–1,40)

1,25(1,07–1,43)

0,68

 LDL-C (mmol/L)

2,77(2,48–3,06)

3,31(2,94–3,68)

3,01(2,46–4,55)

0,31

3,25(3,07–1,43)

4,51(3,54–5,49)

4,74(4,24–5,24)

0,09

 Insulin (%)

46,2

45,4

45,5

0,12

51,4

61,3

62,2

0,09