Maternal diet of polyunsaturated fatty acid altered the cell proliferation in the dentate gyrus of hippocampus and influenced glutamatergic and serotoninergic systems of neonatal female rats

Table 2 Effects of maternal dietary (n-3) PUFA treatment on whole brain fatty acid composition of 1^st-litter neonatal female rats

FA	Percent of Total FA (area percent)
FA	Deficient	Control	Supplementary
C14:0	2.4 ± 0.1	2.1 ± 0.2	2.5 ± 0.0
C16:0	42.5 ± 1.3	39.7 ± 1.1	40.5 ± 0.5
C16:1	3.0 ± 0.0	4.448 ± 0.1	4.5 ± 0.1
C18:0	20.8 ± 0.4*	19.7 ± 0.2	20.2 ± 0.1
C18:1n9c	12.1 ± 0.1**	13.2 ± 0.1	13.7 ± 0.2*
C20:4n6	9.2 ± 0.3	9.4 ± 0.3	7.1 ± 0.5**
C22:6n3	0**	5.3 ± 0.2	7.3 ± 0.3**
Other MUFA	2.9 ± 0.0**	3.1 ± 0.0	3.2 ± 0.1
Other n-6 PUFA	6.2 ± 0.2**	1.5 ± 0.1	0
Total n-3 PUFA	0**	5.2 ± 0.2	7.3 ± 0.4**
Total n-6 PUFA	15.4 ± 0.5**	10.7 ± 0.7	7.2 ± 0.5**
n-3 PUFA/n-6 PUFA	0**	49.2 ± 1.6	105.3 ± 10.2**
DHA/AA	0**	0.56 ± 0.02	1.07 ± 0.07**

Brain FA Composition was expressed as mean ± SEM (n = 5-6 per group). Data were analyzed by variance (ANOVA) for multiple comparisons followed by TUKEY or Dunnett’s t test for post-hoc test. ** p < 0.01, * p < 0.05 vs. Control

ISSN: 1476-511X