Fig. 3From: Secreted frizzled related protein 1 protects H9C2 cells from hypoxia/re-oxygenation injury by blocking the Wnt signaling pathway a Western blot shows that the expression of the anti-apoptotic protein, Bcl2 was reduced and Bax was enhanced by hypoxia and reoxygenation (H+R). These changes were antagonized by Sfrp1-transfected cells before hypoxia and reoxygenation (Sfrp1+H+R). The Wnt signaling pathway activator, Licl, reduced the effects of Sfrp1. b Median values with interquartile range (box) and range (whiskers). Post-hoc analyses of group differences were assessed with Kruskal-Wallis pairwise comparison. Statistical significance was set at the standard level (p<0.05), and the Bonferroni correction was applied in post-hoc analyses (α=0.05/6=0.0083). (Note:* vs. control P<0.001; # vs. H+R P<0.001; vs. Sfrp1+H+R P<0.001)Back to article page