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Fig. 3 | Lipids in Health and Disease

Fig. 3

From: Secreted frizzled related protein 1 protects H9C2 cells from hypoxia/re-oxygenation injury by blocking the Wnt signaling pathway

Fig. 3

a Western blot shows that the expression of the anti-apoptotic protein, Bcl2 was reduced and Bax was enhanced by hypoxia and reoxygenation (H+R). These changes were antagonized by Sfrp1-transfected cells before hypoxia and reoxygenation (Sfrp1+H+R). The Wnt signaling pathway activator, Licl, reduced the effects of Sfrp1. b Median values with interquartile range (box) and range (whiskers). Post-hoc analyses of group differences were assessed with Kruskal-Wallis pairwise comparison. Statistical significance was set at the standard level (p<0.05), and the Bonferroni correction was applied in post-hoc analyses (α=0.05/6=0.0083). (Note:* vs. control P<0.001; # vs. H+R P<0.001; vs. Sfrp1+H+R P<0.001)

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