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Table 4 Changes in ultrasound markers of carotid artery atherosclerosis in subjects with T2DM and without T2DM between the first and second ultrasound examination of the carotid arteries according to rs5498 ICAM genotypes

From: Polymorphism rs5498 of the ICAM-1 gene affects the progression of carotid atherosclerosis in patients with type 2 diabetes mellitus

  KK genotype KE genotype EE genotype p
Subjects with T2DM
Annual CIMT increment (μm/year) 12.76 (5.26–23.96) 20.34 (12.50–28.04) 26.09 (20.69–32.42) 0.04
Δ number of plaque segments 1.0 (0.5–3.0) 2.0 (1.0–2.5) 3.0 (2.0–3.0) 0.65
Δ sum of the plaques thickness (mm) 4.3 (1.4–7.8) 5.4 (1.55–10.15) 6.3 (2.3–8.1) 0.62
Subjects without T2DM
Annual CIMT increment (μm/year) 10.22 (6.72–17.85) 13.47 (10.24–19.66) 16.46 (10.32–21.82) 0.12
Δ number of plaque segments 1.0 (0.5–3.0) 2.0 (1.0–3.0) 2.0 (1.0–3.0) 0.42
Δ sum of the plaques thickness (mm) 2.8 (1.3–6.2) 3.8 (1.40–6.08) 4.5 (1.8–6.64 0.58
  1. Δ- variable value changes during the observation period, expressed as a percentage of baseline values