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Table 5 Association of ICAM-1 polymorphism with carotid atherosclerosis progression in patients with T2DM due to statin treatment

From: Polymorphism rs5498 of the ICAM-1 gene affects the progression of carotid atherosclerosis in patients with type 2 diabetes mellitus

  Statin treatment KK genotype KE genotype EE genotype p
Annual CIMT increment (μm/year) + 11.77 (6.24–16.19) 18.06 (14.45–23.08) 22.62 (17.81–29.48) 0.13
- 14.27 (10.22–19.32) 21.28 (15.21–28.27) 28.04 (24.32–32.56) 0.04
Δ sum of the plaques thickness (mm) + 3.76 (2.8–5.40) 4.69 (3.68–5.12) 5.86 (4.16–7.68) 0.30
- 4.92 (3.76–6.48) 6.40 (4.66–8.02) 6.93 (4.76–8.31) 0.74
Δ number of plaque segments + 1.0 (0.5–2.0) 1.5 (1.0–3.0) 2.0 (1.0–3.0) 0.23
- 1.0 (0.5–2.0) 2.0 (1.0–3.0) 3.0 (0.5–3.0) 0.57