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Table 5 Association of ICAM-1 polymorphism with carotid atherosclerosis progression in patients with T2DM due to statin treatment

From: Polymorphism rs5498 of the ICAM-1 gene affects the progression of carotid atherosclerosis in patients with type 2 diabetes mellitus

 

Statin treatment

KK genotype

KE genotype

EE genotype

p

Annual CIMT increment (μm/year)

+

11.77 (6.24–16.19)

18.06 (14.45–23.08)

22.62 (17.81–29.48)

0.13

-

14.27 (10.22–19.32)

21.28 (15.21–28.27)

28.04 (24.32–32.56)

0.04

Δ sum of the plaques thickness (mm)

+

3.76 (2.8–5.40)

4.69 (3.68–5.12)

5.86 (4.16–7.68)

0.30

-

4.92 (3.76–6.48)

6.40 (4.66–8.02)

6.93 (4.76–8.31)

0.74

Δ number of plaque segments

+

1.0 (0.5–2.0)

1.5 (1.0–3.0)

2.0 (1.0–3.0)

0.23

-

1.0 (0.5–2.0)

2.0 (1.0–3.0)

3.0 (0.5–3.0)

0.57