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Table 7 Relation between genotypes K469E polymorphism for ICAM 1 gene and the progress of carotid artery atherosclerosis in patients with T2DM

From: Polymorphism rs5498 of the ICAM-1 gene affects the progression of carotid atherosclerosis in patients with type 2 diabetes mellitus

  ΔCIMT/year Δ Plaques segments Δ Sum of the plaques thickness
  β p β p β p
Hypertension (0 = no; 1 = yes) 1.45 0.35 1.26 0.64 1.46 0.92
Systolic pressure (mmHg) 0.12 0.44 0.08 0.32 0.45 0.48
Serum LDL (mmol/L) 0.32 0.40 0.07 0.69 0.53 0.41
Serum HDL (mmol/L) −0.04 0.18 −0.51 0.34 −0.39 0.90
Hba1c (%) 0.89 0.70 0.13 0.43 0.68 0.28
KE 1.37 0.49 0.74 0.17 1.14 0.37
EE 3.69 0.03 0.25 0.51 1.31 0.62
  1. All models were adjusted by age, sex, smoking, and treatment with statins
  2. The reference group are homozygotes for allele K