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Table 1 Baseline characteristics of NPHSII compared with the Pakistani cohort

From: Effect of SORT1, APOB and APOE polymorphisms on LDL-C and coronary heart disease in Pakistani subjects and their comparison with Northwick Park Heart Study II

Variable NPHSII samples Pakistani Samples P* P**
Non CHD CHD p-value Non CHD CHD p-value   
Sample number 1770 195   219 404    
Age (years) 55.9 ± 3.4 56.7 ± 3.5 0.0002 56 ± 10.5 59.1 ± 12.6 0.002 0.87 0.01
Sex         
Males (n) 1770 195   119 238 0.27 - -
Females (n) 0 0   100 166    
Diabetes (%) 2.1 5.6 0.006 13.6 64.6 5.1×10-34 2.7x10-19 5.3x10-42
Hypertension (%) 52.6 61.0 0.03 16.4 62.1 8.9x10-28 5.5x10-24 0.80
Smoking (%) 27.8 39.5 0.001 10.5 29.5 7.3x10-08 3.5x10-08 0.01
LDL-C (mmol/l) 3.05 ± 1.01 3.36 ± 0.94 0.00007 2.19 ± 0.44 2.74 ± 0.75 6.5x10-22 1.8x10-34 3.5x10-17
BMI 26.4 ± 3.5 27 ± 3.5 0.019 21.46 ± 9.11 22.46 ± 6.75 0.104   
  1. NPHSII Northwick Park heart study II, CHD coronary heart disease, P* NPHSII non CHD compared with Pakistani non CHD, p** NPHSII CHD compared with Pakistani CHD, LDL-C low density lipoprotein cholesterol, BMI body mass index
  2. Continuous variables are expressed in mean ± standard deviation and categorical variables are expressed in numbers with percentage. P-value: the level of statistical significance