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Table 1 Baseline characteristics of NPHSII compared with the Pakistani cohort

From: Effect of SORT1, APOB and APOE polymorphisms on LDL-C and coronary heart disease in Pakistani subjects and their comparison with Northwick Park Heart Study II

Variable

NPHSII samples

Pakistani Samples

P*

P**

Non CHD

CHD

p-value

Non CHD

CHD

p-value

  

Sample number

1770

195

 

219

404

   

Age (years)

55.9 ± 3.4

56.7 ± 3.5

0.0002

56 ± 10.5

59.1 ± 12.6

0.002

0.87

0.01

Sex

        

Males (n)

1770

195

 

119

238

0.27

-

-

Females (n)

0

0

 

100

166

   

Diabetes (%)

2.1

5.6

0.006

13.6

64.6

5.1×10-34

2.7x10-19

5.3x10-42

Hypertension (%)

52.6

61.0

0.03

16.4

62.1

8.9x10-28

5.5x10-24

0.80

Smoking (%)

27.8

39.5

0.001

10.5

29.5

7.3x10-08

3.5x10-08

0.01

LDL-C (mmol/l)

3.05 ± 1.01

3.36 ± 0.94

0.00007

2.19 ± 0.44

2.74 ± 0.75

6.5x10-22

1.8x10-34

3.5x10-17

BMI

26.4 ± 3.5

27 ± 3.5

0.019

21.46 ± 9.11

22.46 ± 6.75

0.104

  
  1. NPHSII Northwick Park heart study II, CHD coronary heart disease, P* NPHSII non CHD compared with Pakistani non CHD, p** NPHSII CHD compared with Pakistani CHD, LDL-C low density lipoprotein cholesterol, BMI body mass index
  2. Continuous variables are expressed in mean ± standard deviation and categorical variables are expressed in numbers with percentage. P-value: the level of statistical significance