Table 4 Correlation of gene score with LDL-C in both groups
Gene score | NPHSII non CHD | NPHSII CHD | Pakistani non CHD | Pakistani CHD | |
|---|---|---|---|---|---|
Unweighted | Correlation | r = 0.19 | r = 0.11 | r = 0.37 | r = 0.35 |
p-value | 1.4 × 10-16 | 0.12 | 1.6× 10-8 | 4.1× 10-13 | |
▫β(se) | 0.19(0.02) | 0.11(0.07) | 0.17(0.03) | 0.29(0.04) | |
R2 | 3.79 % | 1.26 % | 13.70 % | 12.3 % | |
Weighted | Correlation | R = 0.23 | r = 0.15 | r = 0.33 | r = 0.34 |
p-value | 1.4x10-22 | 0.04 | 5.8 × 10-7 | 9.8x10-13 | |
▪β(se) | 0.22(0.02) | 0.15(0.07) | 0.18(0.03) | 0.31(0.04) | |
R2 | 5.27 % | 2.16 % | 10.88 % | 11.89 % |