Skip to main content

Table 4 Correlation of gene score with LDL-C in both groups

From: Effect of SORT1, APOB and APOE polymorphisms on LDL-C and coronary heart disease in Pakistani subjects and their comparison with Northwick Park Heart Study II

Gene score   NPHSII non CHD NPHSII CHD Pakistani non CHD Pakistani CHD
Unweighted Correlation r = 0.19 r = 0.11 r = 0.37 r = 0.35
p-value 1.4 × 10-16 0.12 1.6× 10-8 4.1× 10-13
▫β(se) 0.19(0.02) 0.11(0.07) 0.17(0.03) 0.29(0.04)
R2 3.79 % 1.26 % 13.70 % 12.3 %
Weighted Correlation R = 0.23 r = 0.15 r = 0.33 r = 0.34
p-value 1.4x10-22 0.04 5.8 × 10-7 9.8x10-13
▪β(se) 0.22(0.02) 0.15(0.07) 0.18(0.03) 0.31(0.04)
R2 5.27 % 2.16 % 10.88 % 11.89 %
  1. r the correlation coefficient, ▫β is the increase in LDL-C per risk allele of unweighted gene score, ▪β is the increase in LDL per SD of weighted gene score, R 2 the proportion of sample variance