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Table 2 Clinical characteristics of the study participants grouped by the number of metabolic syndrome components

From: Association between alpha-fetoprotein and metabolic syndrome in a Chinese asymptomatic population: a cross-sectional study

Variable

No of components of MS

P value

MS 0

MS 1

MS 2

MS 3

MS 4

n

1335

2598

2310

1179

333

<0.001

Age (yr)

43 (18–78)

44 (18–87)

47 (18–82)

51 (26–79) #*$

52 (31–82) #*$△

<0.001

Sex (M/F)

735/600

1296/1302

1356/954

621/558$

201/132*â–³

<0.001

WC (cm)

77 (58–90)

80 (60–123)

88 (60–116)

90 (64–115) #*$

92 (81–115) #*$△

<0.001

BMI (kg/m2)

21.6 (15.6–25)

22.7 (15.9–36.9)

25.1 (17.4–36.7)

26.1 (17.3–35.6) #*$

26.3 (22.9–32.3) #*$△

<0.001

SBP (mmHg)

113 ± 9

119 ± 14

132 ± 17

140 ± 15#*$

150 ± 14#*$△

<0.001

DBP (mmHg)

69 ± 7

73 ± 10

81 ± 12

86 ± 10#*$

90 ± 9#*$△

<0.001

ALT (U/L)

15 (4–69)

17 (5–188)

20 (4–151)

24 (4–123) #*$

30 (10–193) #*$△

<0.001

AST (U/L)

18 (10–48)

19 (9–114)

20 (10–132)

21 (7–62) #*$

23 (11–67) #*$△

<0.001

γ-GT (U/L)

16 (3–377)

20 (5–306)

24 (4–429)

31 (8–816) #*$

50 (10–485) #*$△

<0.001

TG (mmol/L)

0.88 (0.31–1.69)

1.16 (0.3–9.68)

1.3 (0.32–17.1)

1.9 (0.8–16.09) #*$

2.37 (0.81–13.76) #*$△

<0.001

Tch (mmol/L)

4.65 (2.92–7.89)

4.69 (2.13–8.49)

4.71 (2.02–10.3)

4.86 (2.62–9) #*$

5.18 (2.8–8.23) #*$△

<0.001

HDL-c (mmol/L)

1.43 (1.03–2.7)

1.23 (0.57–2.86)

1.17 (0.62–2.27)

1.03 (0.58–2.4) #*$

1.0 (0.67–2) #*$

<0.001

LDL-c (mmol/L)

2.59 (1.26–5.62)

2.59 (0.94–6.32)

2.6 (0.75–6.76)

2.66 (1–6.12) #*$

2.69 (1.35–6.0) #*$

0.001

FPG (mmol/L)

4.73 (3.72–5.57)

4.78 (3.64–13)

4.81 (3.45–16)

5 (3.87–17) #*$

6 (4.44–14) #*$△

<0.001

Cr (mmol/L)

61 (29–100)

67 (33–119)

71 (35–118)

76 (36–114) #*$

72 (44–118) #*$

<0.001

HbA1c (%)

5.5 (3.5–6.1)

5.5 (4.4–10.8)

5.6 (4–11.6)

5.7 (4.2–13) #*$

6.4 (4.7–13) #*$△

<0.001

AFP (ng/ml)

2.3 (0.5–13.2)

2.5 (0.5–11.4)

2.5 (0.5–19.1)

2.7 (0.8–16.6) #*$

2.7 (1.1–10.1) #*$

<0.001

Drinker (%)

13.8

15.3

19.9

27.6 #*$

37.0#*$â–³

<0.001

Smoker (%)

24.3

27.0

28.5

27.2

20.7

0.142

FLD (%)

12.1

22.5

45.5

63.6#*$

60.7#*$

<0.001

  1. P-value: comparison among these five groups; # comparison vs. MS 0 group; * comparison vs. MS 1 group; $ comparison vs. MS 2 group; Δ comparison vs. MS 3 group. WC waist circumference, SBP systolic blood pressure, DBP diastolic blood pressure, BMI body mass index, ALT Alanine aminotransferase, AST aspartate aminotransferase, γ-GT gamma-glutamyltransferase, TG triglycerides, Tch total cholesterol, HDL-c high-density lipoprotein cholesterol, LDL-c low-density lipoprotein cholesterol, FPG fasting plasma glucose, Cr creatinine, HbA1c hemoglobin A1c, AFP alpha-fetoprotein, FLD fatty liver disease