Table 1 Summary of characteristics across included studies (60 studies)
From: The relationship between Lp(a) and CVD outcomes: a systematic review
Study population | Study design (no. stds.) | Age (no. stds.) | Gender (no. stds.) | Ethnicity (no. stds.) | Risk of biasa(no. stds.) | Model type (no. stds.) | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
RCTs | Prospective cohort | Nested case control | < 65 years | ≥ 65 years | Males only | Females only | Males and females | White only | Non-White only | Mixed or not reported/unclear | High | Moderate | Low | Not enough information | Cox proportional hazards | Logistic regression | Conditional &unconditional logistic | Discriminant analysis | Other | Conditional logistic regression | Includes LDL-C as model variable | |
Primary prevention General population (39 studies) | 4 | 25 | 10 | 36 | 3 | 13 | 2 | 24 | 15 | 5 | 19 | 7 | 22 | 2 | 8 | 20 | 11 | 1 | 0 | 0 | 7 | 18 |
Primary prevention High risk population (7 studies) | 1 | 6 | 0 | 7 | 0 | 1 | 0 | 6 | 1 | 2 | 4 | 4 | 1 | 1 | 1 | 4 | 1 | 0 | 0 | 1 | 0 | 1 |
Secondary prevention Previous CVD events (14 studies) | 5 | 8 | 1 | 14 | 0 | 1 | 1 | 11 | 1 | 4 | 9 | 2 | 7 | 2 | 3 | 11 | 3 | 0 | 0 | 1 | 0 | 2 |
TOTAL (out of 60 studies) | 10 | 39 | 11 | 57 | 3 | 15 | 3 | 41 | 17 | 11 | 32 | 13 | 30 | 5 | 11 | 35 | 15 | 1 | 0 | 2 | 7 | 21 |