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Table 2 Levels of lipids and CRP among different APOE genotype carriers

From: Interactive effects of C-reactive protein levels on the association between APOE variants and triglyceride levels in a Taiwanese population

APOE SNP MM Mm mm β (95 % CI) P valuea MM Mm + mm β (95 % CI) P valuea
rs429358 TT (n = 480) CT (n = 96) CC (n = 8)    TT (n = 480) CT + CC (n = 104)   
T-cholesterol (mg/dL) 197.1 ± 35.9 204.2 ± 40.1 210.9 ± 28.2 6.67 (−0.13–13.46) 0.054 197.1 ± 35.9 204.7 ± 39.3 7.03 (−0.56–14.63) 0.069
LDL-C (mg/dL) 114.5 ± 32.4 121.0 ± 35.7 132.1 ± 23.0 7.02 (0.90–13.14) 0.025 114.5 ± 32.4 121.8 ± 34.9 7.06 (0.22–13.91) 0.043
HDL-C (mg/dL) 55.8 ± 14.7 52.3 ± 12.1 51.3 ± 13.3 −0.29 (−0.038 to −0.001) 0.040 55.8 ± 14.7 52.2 ± 12.1 −0.02 (−0.04–0.001) 0.063
Triglyceride (mg/dL) 138.3 ± 119.9 165.1 ± 122.7 138.0 ± 68.5 0.047 (0.004–0.09) 0.034 138.3 ± 119.9 163.0 ± 119.4 0.055 (0.006–0.103) 0.027
CRP (mg/L) 1.12 ± 1.40 0.79 ± 1.19 1.96 ± 1.99 −0.12 (−0.21 to −0.04) 0.005 1.12 ± 1.40 0.88 ± 1.29 −0.17 (−0.27 to −0.08) 3.8 x 10−4
rs7412 CC (n = 496) CT (n = 84) TT (n = 5)    CC (n = 496) CT + TT (n = 89)   
T-cholesterol (mg/dL) 201.0 ± 35.5 184.3 ± 37.9 169.8 ± 65.8 −15.77 (−23.13 to −8.40) 3.01 x 10−5 201.0 ± 35.5 183.5 ± 39.5 −17.08 (−25.08–9.08) 3.2 x 10−5
LDL-C (mg/dL) 118.9 ± 32.1 100.2 ± 31.8 65.0 ± 21.4 −19.82 (−26.36 to −13.28) 4.55 x 10−9 118.9 ± 32.1 98.3 ± 32.3 −20.36 (−27.49–13.24) 3.1 x 10−8
HDL-C (mg/dL) 54.7 ± 14.2 57.8 ± 15.3 50.4 ± 8.5 0.01 (−0.007–0.34) 0.188 54.7 ± 14.2 57.4 ± 15.0 0.02 (−0.005–0.04) 0.129
Triglyceride (mg/dL) 143.6 ± 121.1 133.2 ± 108.9 217.8 ± 176.1 0.001 (−0.046–0.049) 0.957 143.6 ± 121.1 137.9 ± 113.9 −0.009 (−0.06–0.04) 0.730
CRP (mg/L) 1.08 ± 1.33 1.10 ± 1.67 0.75 ± 0.68 −0.12 (−0.11–0.08) 0.709 1.08 ± 1.33 1.08 ± 1.63 −0.01 (−0.11–0.09) 0.795
  1. CI confidence interval, M major allele, m minor allele
  2. aThe multiple linear regressions were adjusted for age, sex, BMI, current smoking status, and anti-hypertensive and anti-diabetic treatments