Table 3 Levels of lipids and CRP among different APOE ε genotypes carriers
APOE ε genotypes | T-cholesterol (mg/dL) | Beta (95 % CI) | P valuea | LDL-C (mg/dL) | Beta (95 % CI) | P valuea | Triglyceride (mg/dL) | Beta (95 % CI) | P valuea | HDL-C (mg/dL) | Beta (95 % CI) | P valuea | CRP (mg/L) | Beta (95 % CI) | P valuea |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ε2 (n = 81) | 181.7 ± 36.2 | 0.03 (0.01–0.04) | 4.24 × 10−5 | 96.5 ± 27.6 | 0.05 (0.03–0.07) | 1.94 × 10−7 | 138.4 ± 114.1 | 0.03 (−0.003–0.06) | 0.054 | 57.3 ± 15.2 | −0.02 (−0.03 to −0.002) | 0.008 | 1.09 ± 1.70 | −0.08 (−0.14 to −0.01) | 0.018 |
ε3 (n = 399) | 200.2 ± 35.1 | 118.1 ± 32.1 | 138.3 ± 121.1 | 55.5 ± 14.7 | 1.13 ± 1.33 | ||||||||||
ε4 (n = 96) | 205.0 ± 36.9 | 122.3 ± 32.0 | 165.5 ± 119.7 | 51.7 ± 11.8 | 0.88 ± 1.33 | ||||||||||
ε2 (n = 81) | 181.7 ± 36.2 | 0.05 (0.03–0.06) | 6.65 × 10−6 | 96.5 ± 27.6 | 0.09 (0.06–0.12) | 5.12 × 10−9 | 138.4 ± 114.1 | 0.01 (−0.05–0.06) | 0.779 | 57.3 ± 15.2 | −0.02 (−0.04–0.01) | 0.172 | 1.09 ± 1.70 | 0.02 (−0.09–0.12) | 0.782 |
Non-ε2 (n = 495) | 201.1 ± 35.5 | 118.9 ± 32.1 | 143.6 ± 121.2 | 54.8 ± 14.2 | 1.08 ± 1.33 | ||||||||||
ε4 (n = 96) | 205.0 ± 36.9 | 0.02 (−0.002–0.03) | 0.068 | 122.3 ± 32.0 | 0.03 (0.004–0.06) | 0.031 | 165.5 ± 119.7 | 0.06 (0.01–0.11) | 0.018 | 51.7 ± 11.8 | −0.02 (−0.04 to −0.001) | 0.020 | 0.88 ± 1.33 | −0.19 (−0.28 to −0.09) | 2.12 × 10−4 |
Non-ε4 (n = 480) | 197.1 ± 35.9 | 114.5 ± 32.4 | 138.3 ± 119.9 | 55.8 ± 14.7 | 1.12 ± 1.40 |