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Table 1 Comparisons of clinical characteristics

From: Obstructive sleep apnea combined dyslipidemia render additive effect on increasing atherosclerotic cardiovascular diseases prevalence

Variables Without OSA Mild Moderate Severe
N 56 74 65 53
Age (years) 49.4 ± 11.6 52.2 ± 13.6 53.3 ± 12.2 55.3 ± 13.1*
Male, n (%) 30(53.6) 41(55.4) 35(53.8) 31(58.5)*
Smoking, n (%) 24(42.9) 37(50.0) 32(49.2) 28(52.8)*
BMI (Kg/m2) 24.2 ± 2.7 25.5 ± 3.5 25.8 ± 4.6 26.3 ± 3.9*
Overweight, n (%) 10(17.9) 30(40.5) 31(47.7) 27(50.9)*
Obesity, n (%) 0(0) 0(0) 3(4.6) 8(15.1)*
Waist-hip ratio 0.90 ± 0.03 0.92 ± 0.05 0.94 ± 0.04 0.96 ± 0.03*
SBP (mm Hg) 132.5 ± 10.2 131.7 ± 12.3 135.8 ± 11.6 138.2 ± 13.4*
DBP (mm Hg) 73.6 ± 8.8 73.2 ± 10.5 77.3 ± 9.1 81.2 ± 10.6*
HR (bpm) 74.2 ± 6.6 80.4 ± 9.2 88.4 ± 9.2 93.6 ± 11.2*
FPG (mmol/L) 6.0 ± 1.1 6.2 ± 1.7 6.4 ± 1.5 6.7 ± 1.6*
HbA1c (%) 6.0 ± 1.3 6.3 ± 1.3 6.6 ± 1.3 6.8 ± 1.5*
TC (mmol/L) 5.3 ± 0.5 5.3 ± 0.4 5.4 ± 0.5 5.5 ± 0.6
TG (mmol/L) 1.3 ± 0.4 1.4 ± 0.4 1.4 ± 0.3 1.5 ± 0.4
LDL-C (mmol/L) 3.1 ± 0.4 3.3 ± 0.4 3.3 ± 0.3 3.5 ± 0.5*
HDL-C (mmol/L) 1.0 ± 0.3 0.9 ± 0.3 0.8 ± 0.3 0.8 ± 0.4
CRP (mg/L) 9.2 ± 1.2 10.8 ± 2.4 12.7 ± 2.6 14.2 ± 3.3*
CHD, n (%) 6(10.7) 10(13.5) 11(16.9) 10(18.9)*
Ischemic stroke, n (%) 3(5.4) 4(5.4) 6(9.2) 6(11.3)*
PAD, n (%) 3(5.4) 3(4.1) 4(6.2) 5(9.4)*
Anti-platelet, n (%) 22(39.3) 34(45.9) 32(49.2) 28(52.8)*
ACEI/ARB, n (%) 26(46.4) 36(48.6) 34(52.3) 29(54.7)*
Statins, n (%) 29(51.8) 37(50.0) 35(53.8) 31(58.5)*
AHI (events/h) 3.2 ± 1.3 12.6 ± 2.3 21.2 ± 3.3 35.4 ± 5.1*
  1. Denote: *P < 0.05 versus other groups; bpm beat per minute, TG triglyceride, HDL-C high density lipoprotein cholesterol, ACEI angiotensin converting enzyme inhibitor, ARB angiotensin receptor blocker