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Table 6 Single factor analysis: association of lipid ratios, TG, clinical features and insulin secretion in different phases

From: The triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio as a predictor of insulin resistance but not of β cell function in a Chinese population with different glucose tolerance status

 

HOMA-β

DI30

(ΔIns30/Glu30)/HOMA-IR

DI120

 

OR (95 % CI)

P-value

OR (95 % CI)

P-value

OR (95 % CI)

P-value

OR (95 % CI)

P-value

Log (TG/HDL-C)

0.46 (0.25–0.83)

0.010*

4.20 (2.22–7.94)

0.000*

2.66 (1.45–4.88)

0.002*

5.67 (2.94–10.92)

0.000*

TC/HDL-C

0.89 (0.74–1.07)

0.226

1.54 (1.26–1.89)

0.000*

1.36 (1.21–1.66)

0.002*

1.61 (1.31–1.97)

0.000*

LDL-C/HDL-C

0.76 (0.58–1.00)

0.050

1.72 (1.30–2.29)

0.000*

1.47 (1.11–1.94)

0.007*

1.80 (1.35–2.40)

0.000*

Log TG

0.41 (0.20–0.83)

0.013*

5.80 (2.68–12.54)

0.000*

3.24 (1.57–6.72)

0.002*

8.01 (3.62–17.72)

0.000*

Log HDL-C

3.95 (0.57–27.31)

0.164

0.15 (0.02–1.09)

0.061

0.26 (0.04–1.82)

0.175

0.07 (0.01–0.52)

0.010*

Sex

2.48 (1.69–3.66)

0.000*

1.30 (0.90–1.90)

0.176

1.39 (0.95–2.04)

0.089

1.57 (1.07–2.30)

0.021*

Age, years

1.05 (1.03–1.07)

0.000*

1.04 (1.02–1.06)

0.000*

1.04 (1.02–1.06)

0.000*

1.05 (1.03–1.07)

0.000*

BMI, kg/m2

0.91 (0.87–0.96)

0.000*

1.10 (1.04–1.15)

0.000*

1.07 (1.02–1.13)

0.006*

1.11 (1.06–1.18)

0.000*

Waist circumference, cm

0.99 (0.97–1.01)

0.270

1.04 (1.02–1.06)

0.000*

1.03 (1.01–1.05)

0.007*

1.03 (1.01–1.06)

0.001*

Hip circumference, cm

0.99 (0.97–1.01)

0.250

1.03 (1.01–1.05)

0.003*

1.02 (1.00–1.04)

0.052

0.01 (1.01–1.04)

0.012*

Systolic BP, mm Hg

1.01 (0.10–1.02)

0.093

1.02 (1.01–1.03)

0.004*

1.01 (1.00–1.02)

0.032*

1.01 (1.00–1.02)

0.009*

Diastolic BP, mm Hg

1.01 (0.99–1.02)

0.513

1.01 (0.99–1.03)

0.414

1.01 (0.99–1.03)

0.281

1.01 (0.99–1.03)

0.276

Diabetes

4.22 (2.51–7.09)

0.000*

129.66 (44.21–380.26)

0.000*

79.69 (30.21–210.23)

0.000*

141.19 (51.76–385.18)

0.000*

Pre-diabetes

2.07 (1.37–3.13)

0.001*

8.80 (5.35–14.46)

0.000*

5.77 (3.62–9.21)

0.000*

14.68 (8.55–25.23)

0.000*

HOMA-IR

0.68 (0.60–0.76)

0.000*

2.98 (2.08–4.28)

0.000*

2.46 (1.70–3.57)

0.000*

3.07 (2.10–4.48)

0.000*

  1. * Significant results: p < 0.05