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Table 3 Significantly upregulated proteins in untreated cells

From: Proteomic profiling of cellular steatosis with concomitant oxidative stress in vitro

Accession

Description

HGNC symbol

Peptide count

Confidence score

P-value

Fold change from LPON

NP_734466.1

histone H2A type 1-A

HIST1H2AA

5

321.3

0.02

4.63

NP_005310.1

histone H1.2

HIST1H1C

11

734.0

0.02

3.30

NP_057395.1

ATPase inhibitor, mitochondrial isoform 1 precursor

ATPIF1

2

53.7

0.05

3.01

NP_002404.1

microsomal glutathione S-transferase 2

MGST2

2

61.3

0.03

2.47

NP_061849.2

sodium-coupled neutral amino acid transporter 2

SLC38A2

2

281.4

0.02

2.34

NP_115520.2

ras-related protein Rab-6C

RAB6C

2

78.7

0.04

2.30

NP_000021.1

serine--pyruvate aminotransferase

AGXT

2

103.1

0.01

2.03

NP_112487.1

SRA stem-loop-interacting RNA-binding protein, mitochondrial precursor

SLIRP

2

118.7

0.04

1.99

NP_003283.2

nucleoprotein TPR

TPR

3

244.9

0.01

1.91

NP_004233.1

high mobility group nucleosome-binding domain-containing protein 3 isoform HMGN3a

HMGN3

2

122.5

0.00

1.89

NP_005313.1

histone H1.5

HIST1H1B

6

464.7

0.02

1.86

NP_001070956.1

protein ALEX isoform f

GNAS

3

104.8

0.02

1.81

NP_001600.1

short/branched chain specific acyl-CoA dehydrogenase, mitochondrial precursor

ACADSB

7

517.8

0.01

1.76

NP_056230.1

brain protein 44

MPC2

2

88.0

0.04

1.76

NP_005361.2

ras-related protein Rab-8A

RAB8A

2

95.4

0.01

1.71

NP_002148.1

10 kDa heat shock protein, mitochondrial

HSPE1

5

356.0

0.00

1.70

NP_006852.1

ras-related protein Rab-35 isoform 1

RAB35

2

92.2

0.03

1.70

NP_003365.1

voltage-dependent anion-selective channel protein 1

VDAC1

8

807.2

0.01

1.68

NP_001139021.1

thioredoxin domain-containing protein 5 isoform 3

TXNDC5

6

387.9

0.02

1.66

NP_002130.2

heterogeneous nuclear ribonucleoprotein G isoform 1

RBMX

11

509.6

0.00

1.63

NP_005349.3

LIM domain only protein 7 isoform 1

LMO7

6

317.6

0.04

1.62

NP_079034.3

agmatinase, mitochondrial precursor

AGMAT

5

338.0

0.00

1.62

NP_002734.2

glucosidase 2 subunit beta isoform 1

PRKCSH

10

506.0

0.00

1.60

NP_057318.2

long-chain-fatty-acid--CoA ligase 5 isoform a

ACSL5

10

561.8

0.01

1.59

NP_005309.1

histone H1.0

H1F0

6

380.0

0.03

1.59

NP_001059.2

DNA topoisomerase 2-beta

TOP2B

2

107.4

0.01

1.57

NP_002851.2

delta-1-pyrroline-5-carboxylate synthase isoform 1

ALDH18A1

20

1184.8

0.00

1.57

NP_006293.2

mannosyl-oligosaccharide glucosidase isoform 1

MOGS

4

173.2

0.01

1.57

NP_059980.2

transmembrane emp24 domain-containing protein 9 precursor

TMED9

3

182.6

0.01

1.57

NP_065737.2

4-aminobutyrate aminotransferase, mitochondrial precursor

ABAT

11

699.1

0.00

1.57

NP_006017.1

histone H1x

H1FX

3

195.5

0.04

1.55

NP_055866.1

endoplasmic reticulum resident protein 44 precursor

ERP44

2

153.0

0.05

1.54

NP_056240.2

DNA-directed RNA polymerase I subunit RPA1

POLR1A

2

42.2

0.01

1.51

NP_057371.2

heterochromatin protein 1-binding protein 3

HP1BP3

4

221.1

0.02

1.51

  1. Thirty-four proteins in Category 1 were significantly upregulated in untreated cells