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Table 4 Summary of enriched GO: Molecular Function terms in LPON treated cells

From: Proteomic profiling of cellular steatosis with concomitant oxidative stress in vitro

Enriched GO: molecular function terms

GO database ID

Log of p-value

Proteins enriched in set

structural constituent of ribosome

GO:0003735

10

MRPS31 RPL13A RPS17 RPS23

RPS3 RPS5 RPS7 RPSA

poly(A) RNA binding

GO:0044822

10

CCT6A DDX5 EEF1A1 EEF2 EIF4A1

EIF5A ENO1 FUBP1 GNB2L1 HDLBP

HSPA1B MRPS31 NME1 PEG10 RPL13A

RPS17 RPS23 RPS3 RPS5 RPS7RPSA

RTCB SLC3A2 SND1 TAF15 TCP1 YWHAE

unfolded protein binding

GO:0051082

5.5252

CCT2 CCT5 CCT6A CCT7 HSPA1B TCP1

carboxylic acid binding

GO:0031406

5.51

AARS AKR1C1 ALB FABP1

HNF4A IGF2R MAT2A YWHAE

organic acid binding

GO:0043177

5.4964

AARS AKR1C1 ALB FABP1 HNF4A

IGF2R MAT2A YWHAE

monocarboxylic acid binding

GO:0033293

5.1232

AKR1C1 ALB FABP1

HNF4A IGF2R

translation factor activity, RNA binding

GO:0008135

4.5729

EEF1A1 EEF2 EIF4A1 EIF5A EIF6

ketosteroid monooxygenase activity

GO:0047086

4.3661

AKR1C1 AKR1C3

indanol dehydrogenase activity

GO:0047718

4.3661

AKR1C1 AKR1C3

androsterone dehydrogenase activity

GO:0047023

4.0662

AKR1C1 AKR1C3

trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity

GO:0047115

4.0662

AKR1C1 AKR1C3

17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity

GO:0047006

4.0662

AKR1C1 AKR1C3

translation elongation factor activity

GO:0003746

3.9915

EEF1A1 EEF2 EIF5A

  1. Overrepresented GO: Molecular Function terms were identified by ToppCluster. HGNC symbol is used to display proteins enriched under the GO term. p-value cutoff for enriched terms was <0.05 with Bonferroni correction applied to minimize false-positive detection