Increased alpha-defensin expression is associated with risk of coronary heart disease: a feasible predictive inflammatory biomarker of coronary heart disease in hyperlipidemia patients

Table 1 General description and clinical manifestations of the study population

Variables	Normal (N) n = 17	Hyperlipidemia (H) n = 17	Coronary Heart Disease (CHD) n = 17	p values
Variables	Normal (N) n = 17	Hyperlipidemia (H) n = 17	Coronary Heart Disease (CHD) n = 17	N vs. H	H vs. CHD	N vs. CHD
Age (years)	42 (23–58)	42 (26–58)	66 (58–78)	0.608	0.000	0.000
TC (mg/dL)	174.5 (156–199)	223 (150–304)	166 (115–259)	0.004	0.008	0.653
TG (mg/dL)	147 (70–162)	166 (103–1181)	92 (72–169)	0.759	0.013	0.025
HDL (mg/dL)	41 (31–56)	45.5 (26–80)	49 (37–75)	0.213	0.496	0.063
LDL (mg/dL)	99 (60–111)	130.5 (63–190)	89 (44–174)	0.072	0.049	0.323

All patients and controls were male. N normal controls, H and CHD patients with hyperlipidemia and coronary heart disease, respectively
Data are shown as medians (ranges). The differences in each variable between two groups (N vs. H, H vs. CHD, and N vs. CHD) were determined using the Mann–Whitney U test. The α level was set at < 0.05 at a 95 % confidence interval. The significantly different variables between groups are shown by p value in bold
TC total cholesterol, TG triglyceride, HDL high-density lipoprotein, LDL low-density lipoprotein

ISSN: 1476-511X