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Table 1 Characteristics and laboratory test findings for each group involved in this study

From: Homocysteine diminishes apolipoprotein A-I function and expression in patients with hypothyroidism: a cross-sectional study

Variables

Control group (n = 94)

SHO (n = 91)

HO (n = 73)

p-value

Sex, M/F

10/84

9/82

8/65

0.973

Age, years

46.78 ± 11.22

45.96 ± 13.97

43.07 ± 13.55

0.077

BMI, km/m2

24.15 ± 3.25

24.57 ± 3.31

24.63 ± 3.19

0.990

CHOL, mmol/l

5.00 ± 1.00

5.09 ± 1.21

5.98 ± 1.67†‡

<0.001**

HDL-C, mmol/l

1.47 ± 0.30

1.47 ± 0.33

1.62 ± 0.40†‡

0.027*

LDL-C, mmol/l

2.89 ± 0.81

3.03 ± 0.95

3.47 ± 1.21†‡

0.001**

TG, mmol/l

1.12 (0.79–1.69)

1.16 (0.78–1.78)

1.28 (0.88–1.76)

0.708

Apo A-I, g/l

1.35 ± 0.27

1.34 ± 0.28

1.49 ± 0.38†‡

0.005**

Apo B, g/l

0.89 ± 0.24

0.92 ± 0.26

1.01 ± 0.34†‡

0.007**

Hcy, μmol/l

13.00 (10.75–15.00)

14.00 (12.00–17.00)†

15.00 (13.00–21.50)†‡

<0.001**

  1. Summary of the clinical characteristics and laboratory test results of the study participants (94 controls, 91 patients with SHO and 73 patients with HO). The data are expressed as means ± SDs unless otherwise indicated. TG and Hcy levels are presented as medians (25th and 75th percentiles). BMI body mass index, CHOL total cholesterol, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, TG triglycerides, Apo A-I apolipoprotein A-I, Apo B apolipoprotein B, Hcy homocysteine. Comparisons among groups were performed using aone-way ANOVA test. Because TG and Hcy levels did not follow a normal distribution, comparisons between groups were performed using the Mann–Whitney U test or Kruskal–Wallis H test. *p < 0.05, **p < 0.01, significantly different among the three groups; †p < 0.05, significantly different compared with the control group; ‡p < 0.05, significantly different compared with the SHO group