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Table 2 Comparison of characteristics and the laboratory test findings for the subgroups of each group

From: Homocysteine diminishes apolipoprotein A-I function and expression in patients with hypothyroidism: a cross-sectional study

Parameters

Control group

SHO group

HO group

 

N-control group (n = 76)

H-control group (n = 18)

N-SHO group (n = 59)

H-SHO group (n = 32)

N-HO group (n = 37)

H-HO group (n = 36)

Sex, M/F

6/70

4/14

6/53

3/29

1/36

7/29

Age, years

46.42 ± 11.21

48.28 ± 11.46

45.41 ± 13.98

46.97 ± 14.10

41.73 ± 10.48

44.44 ± 16.16

BMI, km/m2

23.89 ± 3.09

25.21 ± 3.77

24.22 ± 3.35

25.19 ± 3.19

23.96 ± 3.32

25.32 ± 2.94

CHOL, mmol/l

4.99 ± 1.03

5.03 ± 0.90

4.99 ± 0.85

5.26 ± 1.69

5.73 ± 1.15cd

6.24 ± 2.06ab

HDL-C, mmol/l

1.48 ± 0.31

1.41 ± 0.25

1.54 ± 0.32

1.35 ± 0.31**

1.79 ± 0.34 cd

1.44 ± 0.37**

LDL-C, mmol/l

2.87 ± 0.82

2.97 ± 0.76

2.91 ± 0.72

3.25 ± 1.26

3.36 ± 0.94 cd

3.58 ± 1.43

TG, mmol/l

1.18 (0.78–1.72)

1.11 (0.94–1.55)

1.20 (0.77–1.79)

1.10 (0.79–1.64)

1.03 (0.83–1.63)

1.39 (0.92–2.51)

ApoA-I, g/l

1.38 ± 0.28

1.20 ± 0.17*

1.39 ± 0.27

1.25 ± 0.27*

1.59 ± 0.38 cd

1.39 ± 0.35a*

ApoB, g/l

0.88 ± 0.25

0.89 ± 0.21

0.89 ± 0.22

0.96 ± 0.32

0.99 ± 0.29 c

1.03 ± 0.39

  1. To investigate the association among patient characteristics, blood lipid indexes and HHcy, we subdivided each group of patients into two groups according to the plasma Hcy levels. In the HO group, patients with a plasma level of Hcy > 15 μmol/l were termed the H-HO group (n = 36), while other patients were included in the N-HO group (n = 37). Similarly, we subdivided the SHO group into H-SHO (n = 32) and N-SHO (n = 59) subgroups and subdivided the control group into the H-control (n = 18) and N-control (n = 76) groups. The data are expressed as the means ± SDs unless otherwise indicated. TG is presented as medians (25th and 75th percentiles). Comparisons among groups were performed with independent-samples or one-way ANOVA tests. Because TG did not follow a normal distribution, between-group comparisons were performed using the Mann–Whitney U test or Kruskal–Wallis H test. *p < 0.05, **p < 0.01 indicate a significant difference between two subgroups; a p < 0.05, significantly different compared with the H-control group; b p < 0.05, significantly different compared with the H-SHO group; c p < 0.05, significantly different compared with the N-control group; d p < 0.05, significantly different compared with the N-SHO group