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Table 4 Stratification analysis by age, sex and smoking statue for the association of rs10811656 with CAD

From: Association of rs10811656 on 9P21.3 with the risk of coronary artery disease in a Chinese population

SNPs

Groups

Genotype

Crude OR (95 % CI)

P

Adjusted OR (95 % CI)a

P a

Case

Control

rs10811656

 

CC/CT + TT

    

Age (median)

  < 66 years

43/88

47/88

1.09 (0.66–1.82)

0.73

1.20 (0.69–2.10)

0.521

  ≥ 66 years

60/107

52/56

1.66 (1.01–2.71)

0.045

1.63 (0.98–2.72)

0.061

Sex

 Males

63/128

50/61

1.66 (1.03–2.69)

0.037

1.82 (1.10–3.01)

0.02

 Females

49/83

40/67

0.98 (0.58–1.67)

0.967

1.09 (0.62–1.91)

0.76

Smoking

 Yes

37/72

27/30

1.75 (0.91–3.37)

0.093

2.13 (1.06–4.26)

0.033

 No

66/123

72/114

1.17 (0.77–1.79)

0.447

1.21 (0.77–1.89)

0.398

  1. MAF rs10811656 T = 38.17 %, P for HW = 0.379793
  2. CI confidence interval, OR odds ratio
  3. aAdjusted for age, sex, body mass index, smoking status, hypertension, diabetes and dyslipidemia