Variable | Fish oil | Corn oil | Between Groups | |||||
---|---|---|---|---|---|---|---|---|
Baseline | End of trial | P-value/direction | Baseline | End of trial | P-value/direction | Baseline P-value | End P-value | |
Oxidation marker | ||||||||
 MDA (μmol/l) | 3.41 ± 1.34 | 2.43 ± 0.92 | <0.001 ↓ | 3.41 ± 1.34 | 2.41 ± 1.01 | 0.001 ↓ | 0.957 | 0.926 |
 GSH (mmol/l) | 1.97 ± 0.22 | 2.02 ± 0.17 | 0.200 | 2.01 ± 0.21 | 2.07 ± 0.22 | 0.184 | 0.645 | 0.296 |
 8-OH-dG (pg/ml) | 1.54 ± 0.60 | 1.64 ± 0.74 | 0.315 | 1.68 ± 0.60 | 1.75 ± 0.79 | 0.410 | 0.340 | 0.545 |
 NTBI (μmol/l) | −1.36 ± 4.11 | −1.92 ± 2.58 | 0.248 | −1.25 ± 2.17 | −2.31 ± 1.64 | 0.002↓ | 0.950 | 0.445 |
 FCar (μmol/l) | 18.18 ± 9.78 | 21.19 ± 9.58 | 0.004 ↑ | 20.53 ± 9.78 | 22.23 ± 10.12 | 0.121 | 0.222 | 0.657 |
Haemograms (Unit) RV = Reference value | ||||||||
 Haematocrit % RV = 38–57 | 50.15 ± 4.24 | 47.55 ± 8.95 | 0.096 | 49.22 ± 5.15 | 48.38 ± 5.88 | 0.237 | 0.729 | 0.881 |
 Haemoglobin (g/l) RV = 140–203 | 164.23 ± 14.00 | 162.57 ± 15.19 | 0.453 | 160.41 ± 16.71 | 160.94 ± 19.23 | 0.816 | 0.616 | 0.409 |
 MCV (fl) RV = 67–80 | 69.17 ± 2.15 | 68.73 ± 2.23 | 0.010 ↓ | 69.90 ± 3.11 | 69.76 ± 2.54 | 0.636 | 0.339 | 0.180 |
 MCH (pg) RV = 24–29 | 22.64 ± 0.77 | 22.88 ± 0.87 | 0.003 ↑ | 22.76 ± 0.95 | 23.20 ± 0.97 | <0.001 ↑ | 0.572 | 0.494 |
 MCHC (g/l) RV = 345–367 | 327.33 ± 3.96 | 332.80 ± 5.93 | <0.001 ↑ | 325.81 ± 6.18 | 332.56 ± 6.79 | <0.001 ↑ | 0.379 | 0.364 |
 Platelet (n × 109/l) RV = 102–395 | 304.76 ± 88.37 | 309.83 ± 98.56 | 0.692 | 316.13 ± 93.83 | 288.41 ± 101.68 | 0.029 ↓ | 0.991 | 0.513 |
 RBC (n × 1012/l) RV = 5.3–8.0 | 7.25 ± 0.61 | 7.11 ± 0.74 | 0.198 | 7.04 ± .76 | 6.94 ± 0.84 | 0.319 | 0.474 | 0.291 |
 WBC (n × 109/l) RV = 5.4–17.4 | 8.37 ± 2.27 | 8.20 ± 2.36 | 0.564 | 8.45 ± 3.22 | 8.51 ± 3.31 | 0.913 | 0.712 | 0.975 |
 Neutrophil % RV = 40–80 | 68.97 ± 10.52 | 66.46 ± 14.40 | 0.350 | 69.89 ± 11.30 | 70.56 ± 8.44 | 0.644 | 0.971 | 0.195 |
 Lymphocyte % RV = 10–36 | 18.10 ± 8.61 | 19.68 ± 7.74 | 0.109 | 16.11 ± 7.20 | 16.82 ± 5.88 | 0.482 | 0.504 | 0.166 |
 Monocyte % RV = 0–13 | 3.84 ± 2.50 | 1.77 ± 1.92 | <0.001 ↓ | 4.11 ± 3.02 | 3.06 ± 2.70 | 0.050 ↓ | 0.340 | 0.030 a |
 Eosinophil % RV = 2–10 | 7.59 ± 3.53 | 9.01 ± 4.79 | 0.069 | 8.54 ± 5.33 | 8.42 ± 6.00 | 0.927 | 0.605 | 0.551 |
 Basophil % RV = 0–1 | 1.47 ± 1.22 | 0.62 ± 0.62 | 0.001 | 1.33 ± 1.08 | 1.13 ± 0.96 | 0.396 | 0.882 | 0.012 a |
Blood biochemistry | ||||||||
 Urea (mmol/l) RV = 2.4–8.8 | 5.23 ± 1.61 | 5.48 ± 1.31 | 0.308 | 5.12 ± 1.37 | 5.25 ± 1.80 | 0.695 | 0.430 | 0.536 |
 Creatinine (μmol/l) RV = 57–116 | 86.85 ± 9.36 | 90.65 ± 11.73 | 0.008 ↑ | 88.62 ± 13.34 | 93.51 ± 14.85 | 0.001 ↑ | 0.372 | 0.311 |
 ALP (U/l) RV = 33–215 | 127.83 ± 143.75 | 146.85 ± 170.32 | 0.052 | 147.32 ± 107.88 | 153.70 ± 116.36 | 0.283 | 0.598 | 0.843 |
 ALT (U/l) RV = 18–77 | 52.35 ± 24.24 | 77.22 ± 136.25 | 0.279 | 58.60 ± 26.96 | 58.12 ± 28.77 | 0.888 | 0.452 | 0.414 |
 Albumin (g/l) RV = 30–41 | 33.68 ± 2.02 | 33.77 ± 2.57 | 0.790 | 32.80 ± 2.39 | 33.24 ± 2.51 | 0.160 | 0.129 | 0.385 |
 Total protein (g/l) RV = 58–77 | 63.53 ± 4.07 | 64.42 ± 4.34 | 0.158 | 63.97 ± 3.18 | 64.50 ± 3.59 | 0.469 | 0.990 | 0.932 |
 Glucose (mmol/l) RV = 4.0–6.4 | 5.22 ± 0.38 | 5.34 ± 0.43 | 0.171 | 5.18 ± 0.37 | 5.32 ± 0.47 | 0.041 ↑ | 0.645 | 0.854 |
 Cholesterol (mmol/l) RV = 3.7–9.8 | 6.51 ± 1.90 | 6.94 ± 2.40 | 0.109 | 7.13 ± 1.62 | 7.73 ± 2.03 | 0.011 ↑ | 0.463 | 0.135 |
 Triglycerides (mmol/l) RV = 0.5–1.1 | 0.79 ± 0.37 | 0.71 ± 0.46 | 0.406 | 0.80 ± 0.31 | 0.81 ± 0.36 | 0.854 | 0.299 | 0.335 |