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Table 4 C1065A. Genotype and clinical characteristics of T2DM patients and healthy control

From: A single-nucleotide polymorphism C-724 /del in the proter region of the apolipoprotein M gene is associated with type 2 diabetes mellitus

 

Healthy control

T2DM

P-value

CC

CA + AA

CC

CA + AA

CC vs. (CA + AA) in healthy control

CC vs. (CA + AA) in T2DM patients

N (male/femal)

18/18

22/18

66/49

83/61

0.663

0.968

AGE (yrs)

55.00 ± 8.24

57.35 ± 8.84

57.50 ± 10.41

55.39 ± 12.23

0.236

0.141

SBP (mmHg)

118.31 ± 13.08

116.50 ± 12.62

139.84 ± 22.64

136.01 ± 19.29

0.542

0.142

DBP (mmHg)

76.39 ± 8.38

75.65 ± 7.32

85.13 ± 11.59

82.09 ± 11.10

0.683

0.033

DM duration (yrs)

  

6.32 ± 5.62

6.71 ± 6.00

 

0.600

HbA1c (%)

  

9.80 ± 2.51

9.37 ± 2.45

 

0.171

Cr (umol/L)

66.38 ± 16.05

63.39 ± 13.22

72.97 ± 30.90

76.68 ± 32.38

0.376

0.351

CYS-C (mg/L)

0.97 ± 0.20

0.97 ± 0.22

1.19 ± 0.53

1.16 ± 0.46

0.892

0.581

SOD (U/mL)

107.25 ± 10.84

106.20 ± 10.67

81.30 ± 19.61

82.58 ± 29.86

0.672

0.692

FPG (mmol/L)

5.28 ± 0.38

5.42 ± 0.33

9.92 ± 3.55

9.07 ± 3.10

0.087

0.041

TC (mmol/L)

4.18 ± 0.51

4.33 ± 0.53

4.49 ± 1.44

4.44 ± 1.02

0.206

0.767

TG (mmol/L)

1.16 ± 0.42

1.20 ± 0.42

2.19 ± 1.63

2.20 ± 2.08

0.647

0.957

HDL-C (mmol/L)

1.42 ± 0.20

1.41 ± 0.20

1.20 ± 0.31

1.22 ± 0.32

0.875

0.552

LDL-C (mmol/L)

2.24 ± 0.40

2.38 ± 0.41

2.53 ± 0.82

2.52 ± 0.78

0.142

0.936

ApoA-I (g/L)

1.64 ± 0.25

1.68 ± 0.28

1.27 ± 0.36

1.32 ± 0.31

0.500

0.240

ApoB (g/L)

0.72 ± 0.17

0.77 ± 0.19

0.89 ± 0.32

0.91 ± 0.35

0.232

0.597

LP (a) (mg/L)

117.72 ± 86.94

143.92 ± 132.57

156.66 ± 231.64

157.40 ± 152.60

0.317

0.975

apoM (ng/uL)

24.34 ± 11.02

24.62 ± 11.96

19.21 ± 8.46

20.93 ± 11.10

0.917

0.171

  1. Data are means ± SD. P-Value <0.05 was shown in bold