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Table 5 T855C. Genotype and clinical characteristics of T2DM patients and healthy control

From: A single-nucleotide polymorphism C-724 /del in the proter region of the apolipoprotein M gene is associated with type 2 diabetes mellitus

 

Healthy control

T2DM

P-value

TT

TC + CC

TT

TC + CC

TT vs. (TC + CC) in healthy control

TT vs. (TC + CC) in T2DM patients

N (male/femal)

21/26

19/10

90/72

59/38

0.077

0.406

AGE (yrs)

56.83 ± 9.37

55.28 ± 7.19

56.12 ± 12.14

56.68 ± 10.35

0.447

0.703

SBP (mmHg)

116.28 ± 13.45

119.10 ± 11.64

138.06 ± 20.66

137.13 ± 21.37

0.353

0.732

DBP (mmHg)

75.02 ± 7.37

77.59 ± 8.31

83.54 ± 11.54

83.27 ± 11.22

0.165

0.851

DM duration (yrs)

  

6.41 ± 5.84

6.74 ± 5.84

 

0.657

HbA1c (%)

  

9.61 ± 2.51

9.48 ± 2.44

 

0.663

Cr (umol/L)

62.20 ± 13.06

69.02 ± 16.17

74.91 ± 33.70

75.23 ± 28.29

0.047

0.938

CYS-C (mg/L)

0.95 ± 0.21

0.99 ± 0.21

1.18 ± 0.50

1.16 ± 0.48

0.418

0.789

SOD (U/mL)

106.64 ± 11.45

106.79 ± 9.53

83.19 ± 29.26

80.03 ± 18.55

0.952

0.341

FPG (mmol/L)

5.35 ± 0.36

5.36 ± 0.36

9.42 ± 3.29

9.50 ± 3.41

0.931

0.858

TC (mmol/L)

4.35 ± 0.48

4.12 ± 0.57

4.55 ± 1.36

4.32 ± .94

0.075

0.149

TG (mmol/L)

1.18 ± 0.39

1.18 ± 0.47

2.27 ± 2.03

2.07 ± 1.63

0.956

0.409

HDL-C (mmol/L)

1.42 ± 0.19

1.41 ± 0.22

1.21 ± 0.32

1.22 ± 0.31

0.940

0.810

LDL-C (mmol/L)

2.40 ± 0.37

2.18 ± 0.43

2.56 ± 0.83

2.47 ± 0.74

0.023

0.370

ApoA-I (g/L)

1.67 ± 0.26

1.64 ± 0.28

1.30 ± 0.34

1.28 ± 0.34

0.640

0.713

ApoB (g/L)

0.76 ± 0.18

0.72 ± 0.19

0.94 ± 0.37

0.85 ± 0.27

0.334

0.034

LP (a) (mg/L)

154.47 ± 128.70

94.30 ± 69.74

161.87 ± 219.55

149.06 ± 132.16

0.023

0.603

apoM (ng/uL)

26.63 ± 11.92

21.02 ± 9.87

20.55 ± 10.55

19.53 ± 9.13

0.037

0.427

  1. Data are means ± SD. P-Value <0.05 was shown in bold