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Table 6 T778C. Genotype and clinical characteristics of T2DM patients and healthy control

From: A single-nucleotide polymorphism C-724 /del in the proter region of the apolipoprotein M gene is associated with type 2 diabetes mellitus

 

Healthy control

T2DM

P-value

TT

TC + CC

TT

TC + CC

TT vs. (TC + CC) in healthy control

TT vs. (TC + CC) in T2DM patients

N (male/femal)

29/27

11/9

131/97

18/13

0.805

0.949

AGE (yrs)

55.21 ± 8.76

59.10 ± 7.57

56.12 ± 11.71

56.81 ± 13.34

0.082

0.764

SBP (mmHg)

118.73 ± 12.32

113.50 ± 13.58

136.83 ± 20.59

136.06 ± 24.20

0.117

0.851

DBP (mmHg)

76.57 ± 8.23

74.40 ± 6.34

83.11 ± 11.20

81.97 ± 11.44

0.288

0.598

DM duration (yrs)

  

6.49 ± 5.81

6.41 ± 5.61

 

0.943

HbA1c (%)

  

9.51 ± 2.48

9.58 ± 2.37

 

0.875

Cr (umol/L)

64.42 ± 13.46

65.88 ± 17.78

76.19 ± 33.37

74.30 ± 24.27

0.705

0.761

CYS-C (mg/L)

0.96 ± 0.19

0.98 ± 0.27

1.19 ± 0.53

1.15 ± .38

0.738

0.730

SOD (U/mL)

106.93 ± 10.18

106.05 ± 12.28

80.89 ± 20.97

77.42 ± 24.34

0.755

0.401

FPG (mmol/L)

5.38 ± 0.37

5.28 ± 0.32

9.43 ± 3.38

9.59 ± 3.22

0.249

0.813

TC (mmol/L)

4.24 ± 0.55

4.33 ± 0.45

4.36 ± 0.95

4.05 ± .93

0.525

0.097

TG (mmol/L)

1.16 ± 0.41

1.25 ± 0.45

2.14 ± 1.60

1.98 ± 1.35

0.401

0.596

HDL-C (mmol/L)

1.42 ± 0.20

1.40 ± 0.18

1.20 ± 0.31

1.19 ± 0.37

0.806

0.840

LDL-C (mmol/L)

2.30 ± 0.41

2.35 ± 0.41

2.49 ± 0.76

2.32 ± 0.74

0.596

0.224

ApoA-I (g/L)

1.65 ± 0.24

1.69 ± 0.34

1.28 ± 0.32

1.22 ± 0.32

0.625

0.350

ApoB (g/L)

0.75 ± 0.18

0.75 ± 0.18

0.89 ± 0.31

0.83 ± 0.29

0.950

0.318

LP (a) (mg/L)

121.14 ± 97.43

160.56 ± 148.32

160.62 ± 203.15

156.10 ± 119.13

0.183

0.904

apoM (ng/uL)

23.35 ± 10.91

27.68 ± 12.58

20.05 ± 10.21

18.20 ± 8.53

0.148

0.337