Relationship between plasma lipids and mild cognitive impairment in the elderly Chinese: a case-control study

Table 1 Principal characteristics and lipid profile of MCI and cognitively normal controls

Characteristics	MCI group (n = 112)	Control group (n = 115)	P value
Age, years (Mean ± SD)^b	76.32 ± 5.73^*	74.51 ± 6.02	0.023
Female gender (%)^a	79 (70.54)^*	55 (47.83)	0.002
Education, years (Mean ± SD)^b	8.62 ± 4.63^*	9.12 ± 4.51	0.017
MMSE scores (Mean ± SD)^b	17.25 ± 4.28^*	25.22 ± 3.25	0.001
BMI (kg/m²) (Mean ± SD)^b	25.51 ± 4.62^*	27.41 ± 5.41	0.004
Current smoking (%)^a	11 (9.82)	13 (11.30)	0.783
Lipid level (mg/dl)^b
TC (Mean ± SD)	196.61 ± 17.22^*	190.21 ± 20.92	0.012
TG (Mean ± SD)	147.53 ± 27.52^*	156.52 ± 28.51	0.018
HDL-C (Mean ± SD)	46.72 ± 5.51^*	48.61 ± 5.82	0.014
LDL-C (Mean ± SD)	118.62 ± 34.31	120.22 ± 36.41	0.742
Vascular disorders (%)^a
Stroke	19 (18.96)	15 (7.04)	0.321
T2DM	32 (28.57)^*	17 (14.78)	0.013
Hypertension	73 (65.18)^*	48 (41.74)	0.001
Heart disease	42 (37.50)^*	27 (23.48)	0.031

Figures in parentheses indicate percentages; Values for continuous variables are mean ± standard deviation
Abbreviations: BMI Body Mass Index, HDL-C High-density lipoprotein cholesterol, LDL-C Low-density lipoprotein cholesterol, T2DM diabetes mellitus type II, TC Total Cholesterol, TG Triglyceride
*significant at P < 0.05 vs control group
^aDichotomous variables (n, %) were tested using χ ² test
^bContinuous variables (mean, SD) were tested for differences between the two groups using Mann–Whitney or t-test

ISSN: 1476-511X