Fig. 4
From: Clinical assessment of hepatic de novo lipogenesis in non-alcoholic fatty liver disease
De novo fatty acids. The saturated fatty acid palmitic acid is the main product of fatty acid synthase. Long-chain elongase (LCE) can extend palmitic acid by 2-carbons to generate stearic acid. Palmitic and stearic acids serve as precursors for palmitoleic and oleic fatty acids respectively, where a double bond is incorporated into the fatty acid chain by sterol-CoA desaturase (SCD)