Skip to main content

Table 2 Blood lipid profile of various groups after 12 weeks of study duration

From: Synergistic combinatorial antihyperlipidemic study of selected natural antioxidants; modulatory effects on lipid profile and endogenous antioxidants

Parameters

GROUP

TC value (mg dl−1) ± SEM

LDL-C value (mg dl−1) ± SEM

HDL-C value (mg dl−1) ± SEM

TG value (mg dl−1) ± SEM

VLDL-C (mg dl−1) Value ± SEM

LDL/HDL ratio ± SEM

Atherogenic index ± SEM

1

Blank Control

105 ± 5.013

58.75 ± 18.25

30.65 ± 1.74

78 ± 3.527

35.45 ± 3.074

1.917 ± 0.56

0.406 ± 0.037

2

Disease Control

946 ± 38.53

848.8 ± 34.19

27.83 ± 0.82

347 ± 10.04

157.7 ± 2.29

30.50 ± 0.69

1.096 ± 0.040

3

Atorvastatin

***

625 ± 17.42

***

539.65 ± 15.01

***

37.35 ± 1.72

***

240 ± 5.49

***

109.1 ± 3.35

***

14.45 ± 0.99

***

0.808 ± 0.061

4

Proanthocyanidins (OPC)

***

733 ± 21.42

***

647.8 ± 19.34

ns

33.24 ± 2.09

***

260 ± 9.10

***

118.2 ± 2.09

***

19.49 ± 0.87

**

0.893 ± 0.033

5

Nicotinic acid (NA)

**

806 ± 16.51

**

715.1 ± 19.87

*

35.29 ± 1.85

**

278 ± 8.66

**

126.4 ± 4.79

***

20.26 ± 0.94

**

0.896 ± 0.053

6

Pterostilbene (PT)

***

698 ± 14.19

***

607.16 ± 14.45

ns

31.64 ± 3.03

*

296 ± 3.64

*

134.5 ± 6.30

***

19.19 ± 0.91

*

0.971 ± 0.073

7

OPC : NA (30:70)

***

725 ± 15.92

***

635.1 ± 14.62

***

37.86 ± 1.88

***

260 ± 6.26

***

118.2 ± 3.93

***

16.77 ± 0.69

***

0.837 ± 0.045

8

OPC : NA (50:50)

***

704 ± 13.15

***

614.0 ± 12.58

*

35.42 ± 1.36

***

273 ± 8.68

**

124.1 ± 3.76

***

17.33 ± 0.75

**

0.887 ± 0.037

9

OPC : NA (70:30)

***

642 ± 13.31

***

555.4 ± 11.65

*

36.16 ± 2.13

***

252 ± 8.54

***

114.5 ± 3.38

***

15.36 ± 0.98

***

0.843 ± 0.041

10

OPC : PT (30:70)

***

598 ± 14.01

***

507.8 ± 10.38

ns

33.42 ± 1.68

**

284 ± 3.81

*

129.1 ± 4.17

***

15.19 ± 0.42

*

0.929 ± 0.057

11

OPC : PT (50:50)

***

642 ± 15.60

***

553.5 ± 14.66

ns

33.89 ± 2.12

***

273 ± 8.68

**

124.1 ± 3.76

***

16.33 ± 0.75

**

0.906 ± 0.037

12

OPC : PT (70:30)

***

608 ± 15.06

***

518.0 ± 12.37

*

35.47 ± 2.16

***

252 ± 8.95

***

114.5 ± 3.38

***

14.60 ± 0.98

**

0.851 ± 0.041

13

NA : PT (30:70)

***

615 ± 15.02

***

526.2 ± 9.57

ns

33.41 ± 1.61

***

277 ± 11.1

**

125.9 ± 3.04

***

15.75 ± 0.53

*

0.919 ± 0.037

14

NA : PT (50:50)

***

646 ± 13.97

***

555.4 ± 12.30

**

36.63 ± 1.54

***

270 ± 7.07

**

122.7 ± 4.34

***

15.16 ± 0.84

**

0.868 ± 0.037

15

NA : PT (70:30)

***

659 ± 13.11

***

567.6 ± 10.70

**

37.44 ± 2.26

***

270 ± 5.91

**

122.7 ± 3.86

***

15.16 ± 0.89

***

0.858 ± 0.053

16

OPC : NA : PT (50:30:20)

***

563 ± 13.31

***

474.2 ± 11.55

***

38.20 ± 1.89

***

253 ± 6.65

***

115.0 ± 3.04

***

12.41 ± 0.72

***

0.821 ± 0.041

17

OPC : NA : PT (50:20:30)

***

572 ± 13.15

***

482.67 ± 8.29

**

37.53 ± 1.34

***

259 ± 9.46

**

120.5 ± 5.08

***

12.86 ± 0.78

***

0.839 ± 0.037

18

OPC : NA : PT (20:50:30)

***

588 ± 11.73

***

497.32 ± 13.06

***

38.68 ± 2.37

***

260 ± 2.81

***

118.2 ± 2.83

***

12.86 ± 1.17

**

0.827 ± 0.029

  1. For a group of six animals, the lipid profiles were calculated as mean ± SEM. Treatment groups were compared with the disease control using ANOVA followed by Dunnet’s test (*p <0.05, ** p <0.01, ***p <0.001)