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Table 1 The comparison of clinical characteristics and plasma parameters include apoM

From: Effects of hyperlipidaemia on plasma apolipoprotein M levels in patients with type 2 diabetes mellitus: an independent case–control study

  Healthy controls (n =105) Hyperlipidaemia (n = 79) T2DM without hyperlipidaemia (n = 125) T2DM with hyperlipidaemia (n =98) P value
N (male/femal) 56/49 45/34 72/53 60/38 0.729
AGE (yrs) 54.65 ± 10.20 53.70 ± 10.61 55.30 ± 12.32 54.82 ± 11.79 0.805
SBP (mmHg) 118.00 ± 12.71 122.94 ± 14.01a 133.59 ± 18.36aaa 137.47 ± 19.74aaaccc 0.000
DBP (mmHg) 76.25 ± 8.37 81.15 ± 10.81aa 82.74 ± 10.84aaa 84.86 ± 10.27aaac 0.000
DM duration (yrs) - - 6.00 ± 5.55 6.46 ± 6.25  
HbA1c (%(mmol/mol)) - - 9.3 ± 2.7(78 ± 30) 9.6 ± 2.0(81 ± 22)  
Cr (umol/L) 63.88 ± 14.76 71.42 ± 14.69aa 66.88 ± 19.62 70.81 ± 26.75a 0.026
CYS-C (mg/ L) 0.98 ± 0.22 1.02 ± 0.28 1.00 ± 0.25bb 1.13 ± 0.39aaac 0.001
SOD (U/mL) 108.82 ± 10.88 103.85 ± 15.70 81.90 ± 19.01aaa 88.82 ± 32.17aaaccc 0.000
FPG (mmol/L) 5.35 ± 0.40 5.32 ± 0.65 8.72 ± 3.09aaabbb 10.14 ± 3.22aaaccc 0.000
TC (mmol/L) 4.31 ± 0.57 4.85 ± 1.23aa 4.00 ± 0.85abbb 5.00 ± 1.53aaa 0.000
TG (mmol/L) 1.19 ± 0.45 3.19 ± 0.97aaa 1.27 ± 0.50bbb 3.50 ± 1.19aaac 0.000
HDL-C (mmol/L) 1.43 ± 0.24 1.22 ± 0.22aaa 1.26 ± 0.34aaabbb 1.12 ± 0.25aaac 0.000
LDL-C (mmol/L) 2.33 ± 0.44 2.20 ± 0.90 2.36 ± 0.69b 2.62 ± 0.93aaccc 0.002
apoA-I (g/L) 1.66 ± 0.29 1.86 ± 0.31aaa 1.28 ± 0.31aaa 1.29 ± 0.33aaaccc 0.000
apoB (g/L) 0.78 ± 0.22 1.11 ± 0.20aaa 0.77 ± 0.26bbb 1.04 ± 0.36aaa 0.000
LP(a) (mg/L) 124.24 ± 106.99 102.60 ± 109.03 143.13 ± 133.09 126.92 ± 140.27 0.160
  1. Data mean ± SD. N number, M male, F female, SBP systolic blood pressure, DBP diastolic blood pressure, HbA1c glycated hemoglobin A1c, is presented as NGSP units (%) and with IFCC units (mmol/mol) in parentheses., apo apolipoprotein; P value comparisons among four groups by one-way ANOVA, avs. healthy control group, a P <0.05, aa P <0.01, aaa P <0.001, bvs. T2DM with hyperlipidaemia group, b P <0.05, bb P <0.01, bbb P <0.001, cvs. hyperlipidaemia group, c P <0.05, cc P <0.01, ccc P <0.001