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Fig. 2 | Lipids in Health and Disease

Fig. 2

From: Advanced glycation end products increase lipids accumulation in macrophages through upregulation of receptor of advanced glycation end products: increasing uptake, esterification and decreasing efflux of cholesterol

Fig. 2

AGEs increase lipid accumulation in macrophages in a concentration-dependent manner. a–d Representative images of oil red staining. a control group; b AGEs of 300 μg/ml group; c AGEs of 600 μg/ml group; d AGEs of 600 μg/ml plus anti-RAGE antibody group. The magnification of each panel is 200×. e Quantification of Oil Red O stained cells as measured by the OD value at 518 nm. The results were normalized as OD value/number of cells. Data represent mean ± SD. from three independent experiments, each performed in triplicate. *P < 0.05 vs. 600 μg/ml AGEs group. One of three representative experiments is shown

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