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Fig. 6 | Lipids in Health and Disease

Fig. 6

From: Advanced glycation end products increase lipids accumulation in macrophages through upregulation of receptor of advanced glycation end products: increasing uptake, esterification and decreasing efflux of cholesterol

Fig. 6

AGEs downregulate ABCG1 expression in macrophages. The expression of ABCA1, ABCG1, LXR-α mRNA (a–c) and protein (d–f) were determined using real-time quantitative PCR and western blotting assays, respectively. All the results are expressed as mean ± SD, from three independent experiments, each performed in triplicate. *P < 0.05 vs. control group. Δ P < 0.05 vs. 600 μg/ml of AGEs group

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Lipids in Health and Disease

ISSN: 1476-511X