Advanced glycation end products increase lipids accumulation in macrophages through upregulation of receptor of advanced glycation end products: increasing uptake, esterification and decreasing efflux of cholesterol

Table 1 Effects of AGEs on cholesterol content in macrophages. (ng/μg protein)

	Control	300 μg/ml of AGEs	600 μg/ml of AGEs	600 μg/ml of AGEs + Anti-RAGE antibody
TC	197.13 ± 22.1**	234.43 ± 11.23**	652.61 ± 11.76*	407.78 ± 33.98^, *
FC	163.21 ± 7.42**	201.83 ± 12.44**	458.70 ± 29.14*	284.20 ± 33.57^, *
CE	33.92 ± 29.49**	32.6 ± 20.02**	193.91 ± 31.39*	123.58 ± 65.19^, *

Data are expressed as mean ± S.D. *P < 0.05 vs. control group, **P < 0.05 vs. 600 μg/ml of AGEs group

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