Fig. 4
From: Stimulating effect of normal-dosing of fibrates on cell proliferation: word of warning
Expression of CYP2J2 in HEK293, HepG2, and HT-29 cell lines in control cells and after fibrates treatment in concentration which promotes viability and IC10. Generally, in maximal viability concentrations, CYP2J2 protein expression is elevated in all tested cell lines. In IC10 concentrations, CYP2J2 is returned to control levels or slightly downregulated. The higher expression of CYP2J2 could explain increase in viability of the cells. Detection of GAPDH expression was used as endogenous control. Relative protein expression was evaluated by measuring optical density (OD)