Fig. 4

Blood serum and NAF estrogen levels. 17-β-estradiol was measured by radioimmunoassay at baseline and 3 MC after each intervention or washout period. a Average E2 levels ± SE in serum (n = 41). b Average E2 levels ± SE in NAF expressed per μg protein (n = 15). c correlation between serum and NAF E2 concentrations. Points represent the serum E2 value plotted as a function of the corresponding NAF value. a = different from baseline by ANOVA and Tukey's post-hoc test (p < 0.05)