Table 1 Clinical and genetic characteristics of the study population

 Age, years

59.88 ± 12.58

64.63 ± 9.51

0.001

59.14 ± 9.69

64.48 ± 8.30

 Weight, kg

65.35 ± 9.43

65.58 ± 8.54

0.863

59.65 ± 9.39

59.15 ± 9.09

 BMI, kg/m²

23.58 ± 3.13

24.04 ± 3.03

0.311

24.26 ± 3.58

24.42 ± 3.68

 Menopause, n (%)

NA

NA

62 (86.11)

115 (95.83)

 Dyslipidemia, n (%)

49 (60.49)

155 (75.61)

0.011

32 (44.44)

73 (60.83)

 Hypertension, n (%)

29 (35.80)

117 (57.07)

0.001

27 (37.50)

68 (56.67)

 Diabetes, n (%)

9 (11.11)

27 (13.17)

0.636

6 (8.33)

23 (19.17)

 TG, mmol/L

1.27 ± 0.67

1.58 ± 1.31

0.056

1.42 ± 0.68

1.75 ± 1.10

 TC, mmol/L

3.87 ± 1.01

4.13 ± 1.21

0.087

4.11 ± 1.03

4.40 ± 1.14

 LDL-C, mmol/L

2.54 ± 1.85

2.61 ± 0.95

0.662

2.45 ± 0.77

2.77 ± 0.93

 HDL-C, mmol/L

1.03 ± 0. 29

0.95 ± 0.23

0.010

1.11 ± 0.26

1.06 ± 0.24

 ApoAI, g/L

1.08 ± 0.16

1.01 ± 0.20

0.002

1.13 ± 0.19

1.11 ± 0.18

 ApoB, g/L

0.73 ± 0.24

0.81 ± 0.29

0.022

0.75 ± 0.23

0.84 ± 0.27

 Lp(a), mg/L

264.04 ± 320.60

310.96 ± 332.45

0.140

239.74 ± 249.33

322.45 ± 340.38

 TG/HDL-C

1.41 ± 1.03

1.82 ± 1.55

0.036

1.38 ± 0.83

1.85 ± 1.60

 TC/HDL-C

3.94 ± 1.26

4.52 ± 1.35

0.001

3.75 ± 0.75

4.30 ± 1.31

 LDL-C/HDL-C

2.55 ± 1.51

2.87 ± 1.10

0.052

2.24 ± 0.65

2.73 ± 1.08

 ApoB/apoAI

0.68 ± 0.25

0.85 ± 0.46

0.002

0.66 ± 0.19

0.78 ± 0.28

 TT, n (%)

43 (53.09)

103 (50.24)

0.751

42 (58.33)

63 (52.50)

 TC, n (%)

33 (40.74)

90 (43.90)

28 (38.89)

51 (42.50)

 CC, n (%)

5 (6.17)

12 (5.85)

2 (2.78)

6 (5.00)

 T allele

0.735

0.722

0.761

0.778

0.738

 C allele

0.265

0.278

0.222

0.263