From: Relationship between oxysterols and mild cognitive impairment in the elderly: a case–control study
MCI | Controls | P value | |||
---|---|---|---|---|---|
(n = 70) | (n = 140) | ||||
Demographic and risk factors | |||||
Age (y) | 59 | (61–72) | 60 | (62–69) | – |
Male, % | 50.0 | 50.0 | – | ||
Education (y) | – | ||||
≤ 9, (%) | 44.3 | 44.3 | |||
9 ~ 12, (%) | 25.7 | 25.7 | |||
≥ 12, (%) | 30.0 | 30.0 | |||
Smokers, % | 32.9 | 22.9 | 0.12a | ||
Drinkers, % | 22.9 | 37.9 | 0.03a | ||
Hypertension, % | 41.4 | 41.4 | 1.00a | ||
Coronary Heart Disease, % | 7.1 | 8.6 | 0.72a | ||
Diabetes, % | 20.0 | 12.1 | 0.13a | ||
Cerebrovascular Disease, % | 2.9 | 2.9 | 1.00a | ||
BMI (kg/m2) | 24.42 | ±2.53 | 25.25 | ±3.78 | 0.10b |
MCI screening | |||||
MMSE scores | 28 | (27–29) | 28 | (27–30) | 0.07 c |
MoCA scores | 22 | (19–23) | 26 | (25–28) | <0.01c |
Laboratory | |||||
FBG (mmol/L) | 5.58 | (5.20–6.25) | 5.54 | (5.09–6.14) | 0.38c |
TG (mmol/L) | 1.38 | (0.97–2.03) | 1.41 | (1.01–2.07) | 0.69c |
HDL-C (mmol/L) | 1.4 | (1.18–1.60) | 1.4 | (1.10–1.53) | 0.71c |
LDL-C (mmol/L) | 2.57 | ±0.75 | 2.76 | ±0.74 | 0.09b |
TC (mmol/L) | 4.56 | ±1.00 | 4.73 | ±0.85 | 0.20b |
Aβ1-40 (pg/mL) | 992.08 | ±208.92 | 589.08 | ±214.39 | <0.01b |
Aβ1-42 (pg/mL) | 795.01 | ±177.43 | 451.54 | ±209.08 | <0.01b |