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Table 1 Demographic and clinical characteristics of MCI patients and controls

From: Relationship between oxysterols and mild cognitive impairment in the elderly: a case–control study

 

MCI

 

Controls

 

P value

 

(n = 70)

 

(n = 140)

  

Demographic and risk factors

 Age (y)

59

(61–72)

60

(62–69)

 Male, %

50.0

 

50.0

 

 Education (y)

    

   ≤ 9, (%)

44.3

 

44.3

  

  9 ~ 12, (%)

25.7

 

25.7

  

   ≥ 12, (%)

30.0

 

30.0

  

 Smokers, %

32.9

 

22.9

 

0.12a

 Drinkers, %

22.9

 

37.9

 

0.03a

 Hypertension, %

41.4

 

41.4

 

1.00a

 Coronary Heart Disease, %

7.1

 

8.6

 

0.72a

 Diabetes, %

20.0

 

12.1

 

0.13a

 Cerebrovascular Disease, %

2.9

 

2.9

 

1.00a

 BMI (kg/m2)

24.42

±2.53

25.25

±3.78

0.10b

MCI screening

 MMSE scores

28

(27–29)

28

(27–30)

0.07 c

 MoCA scores

22

(19–23)

26

(25–28)

<0.01c

Laboratory

 FBG (mmol/L)

5.58

(5.20–6.25)

5.54

(5.09–6.14)

0.38c

 TG (mmol/L)

1.38

(0.97–2.03)

1.41

(1.01–2.07)

0.69c

 HDL-C (mmol/L)

1.4

(1.18–1.60)

1.4

(1.10–1.53)

0.71c

 LDL-C (mmol/L)

2.57

±0.75

2.76

±0.74

0.09b

 TC (mmol/L)

4.56

±1.00

4.73

±0.85

0.20b

 Aβ1-40 (pg/mL)

992.08

±208.92

589.08

±214.39

<0.01b

 Aβ1-42 (pg/mL)

795.01

±177.43

451.54

±209.08

<0.01b

  1. a Data presented as frequencies (percentages) were compared between 2 groups by using Chi-square test
  2. b Data presented as means ± standard deviations were compared between 2 groups by using the Student t–test
  3. c Data presented as medians (interquartile ranges) were compared between 2groups by using the Mann Whitney U test