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Table 2 Cytotoxic activity of the oil of P. aequale on cancer cell linesa

From: Composition and cytotoxic and antioxidant activities of the oil of Piper aequale Vahl

Sample

 

IC50 (μg/ml)a

 

Hemolysis

 

HCT-116 (Colon)

SKMEL19 (Melanoma)

ACP-03 (Gastric)

(μg/ml)

Oil

8.69 (7.20–10.50)

> 25

1.54 (1.34–1.77)

> 200

Doxorubicin

0.10 μM (0.05–0.28)

0.3 μM (0.24–0.38)

0.27 μM (0.22–0.33)

> 200

  1. aData are presented as IC50 values and 95 % confidence intervals obtained by nonlinear regression for all cell lines from three independent experiments. Doxorubicin (DOX) was used as positive control. Only compounds with IC50 values lower than 25 μg/mL in at least one cell line were considered active
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Lipids in Health and Disease

ISSN: 1476-511X