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Table 3 Associations between selected single nucleotide polymorphisms and plasma lipid concentrations

From: Association of KCTD10, MVK, and MMAB polymorphisms with dyslipidemia and coronary heart disease in Han Chinese population

Polymorphisms

TC (mmol/L)

P a

TG (mmol/L)

P a

HDL-C (mmol/L)

P a

rs1477117 (G > A)

 GG (n = 605)

4.17 ± 0.80

0.143

1.86 ± 1.49

0.848

1.34 ± 0.55

0.456

 GA (n = 238)

4.11 ± 0.80

1.91 ± 1.58

1.35 ± 0.59

 AA (n = 11)

3.68 ± 0.63

0.94 ± 0.50

1.68 ± 0.50

 GG (n = 605)

4.17 ± 0.80

0.255

1.86 ± 1.49

0.733

1.34 ± 0.55

0.812

 GA + AA (n = 249)

4.09 ± 0.80

1.87 ± 1.56

1.36 ± 0.59

 GG + GA (n = 843)

4.15 ± 0.80

0.081

1.88 ± 1.52

0.028

1.34 ± 0.56

0.024

 AA (n = 11)

3.68 ± 0.63

0.94 ± 0.50

1.68 ± 0.50

rs11066782 (C > T)

 CC (n = 594)

4.19 ± 0.80

0.035

1.90 ± 1.50

0.319

1.33 ± 0.55

0.065

 CT (n = 248)

4.07 ± 0.79

1.85 ± 1.58

1.38 ± 0.60

 TT (n = 12)

3.82 ± 0.77

0.93 ± 0.48

1.71 ± 0.49

 CC (n = 594)

4.19 ± 0.80

0.052

1.90 ± 1.50

0.653

1.33 ± 0.55

0.197

 CT + TT (n = 260)

4.06 ± 0.79

1.80 ± 1.56

1.39 ± 0.59

 CC + CT (n = 842)

4.15 ± 0.80

0.202

1.89 ± 1.52

0.015

1.34 ± 0.56

0.007

 TT (n = 12)

3.82 ± 0.77

0.93 ± 0.48

1.71 ± 0.49

rs11613718 (C>T)

 CC (n = 580)

4.18 ± 0.79

0.025

1.88 ± 1.50

0.599

1.33 ± 0.55

0.243

 CT (n = 259)

4.07 ± 0.78

1.86 ± 1.56

1.37 ± 0.59

 TT (n = 10)

3.71 ± 0.66

0.96 ± 0.52

1.70 ± 0.53

 CC (n = 580)

4.18 ± 0.79

0.042

1.88 ± 1.50

0.914

1.33 ± 0.55

0.461

 CT + TT (n = 269)

4.05 ± 0.78

1.83 ± 1.55

1.38 ± 0.59

 CC + CT (n = 839)

4.15 ± 0.79

0.131

1.88 ± 1.52

0.053

1.34 ± 0.56

0.031

 TT (n = 10)

3.71 ± 0.66

0.96 ± 0.52

1.70 ± 0.53

rs11615336 (C > A)

 CC (n = 599)

4.19 ± 0.80

0.005

1.90 ± 1.51

0.191

1.34 ± 0.55

0.275

 CA (n = 221)

4.03 ± 0.75

1.80 ± 1.53

1.36 ± 0.60

 AA (n = 11)

3.68 ± 0.63

0.94 ± 0.50

1.68 ± 0.50

 CC (n = 599)

4.19 ± 0.80

0.009

1.90 ± 1.51

0.392

1.34 ± 0.55

0.546

 CA + AA (n = 232)

4.02 ± 0.75

1.76 ± 1.51

1.38 ± 0.60

 CC + CA (n = 820)

4.15 ± 0.79

0.082

1.87 ± 1.51

0.031

1.34 ± 0.56

0.025

 AA (n = 11)

3.68 ± 0.63

0.94 ± 0.50

1.68 ± 0.50

rs12817689 (A > G)

 AA (n = 603)

4.18 ± 0.80

0.038

1.89 ± 1.50

0.733

1.34 ± 0.55

0.423

 AG (n = 218)

4.06 ± 0.78

1.90 ± 1.58

1.35 ± 0.60

 GG (n = 13)

3.88 ± 0.67

1.34 ± 1.20

1.54 ± 0.57

 AA (n = 603)

4.18 ± 0.80

0.051

1.89 ± 1.50

0.995

1.34 ± 0.55

0.669

 AG + GG (n = 231)

4.05 ± 0.77

1.87 ± 1.56

1.36 ± 0.60

 AA + AG (n = 821)

4.14 ± 0.79

0.278

1.89 ± 1.52

0.172

1.34 ± 0.56

0.099

 GG (n = 13)

3.88 ± 0.67

1.34 ± 1.20

1.54 ± 0.57

rs11067233 (C > G)

 CC (n = 644)

4.15 ± 0.80

0.392

1.94 ± 1.54

0.123

1.32 ± 0.56

0.049

 CG (n = 192)

4.17 ± 0.82

1.68 ± 1.46

1.44 ± 0.55

 GG (n = 10)

4.10 ± 0.63

1.38 ± 1.12

1.51 ± 0.42

 CC (n = 644)

4.15 ± 0.80

0.347

1.94 ± 1.54

0.137

1.32 ± 0.56

0.047

 CG + GG (n = 202)

4.17 ± 0.81

1.66 ± 1.44

1.44 ± 0.55

 CC + CG (n = 836)

4.15 ± 0.80

0.952

1.88 ± 1.52

0.482

1.35 ± 0.56

0.591

 GG (n = 10)

4.10 ± 0.63

1.38 ± 1.12

1.51 ± 0.42

  1. TC total cholesterol, TG triglycerides, HDL-C high-density lipoprotein-cholesterol
  2. aMultiple linear regression with adjustment for sex, age, smoking and BMI
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Lipids in Health and Disease

ISSN: 1476-511X