Skip to main content

Table 4 Associations between selected single nucleotide polymorphisms and risk of coronary heart disease

From: Association of KCTD10, MVK, and MMAB polymorphisms with dyslipidemia and coronary heart disease in Han Chinese population

Gene

SNP

Casesa

Controlsa

MAF

Heterozygote vs. major homozygote

Minor homozygote vs. major homozygote

Additive model

(N = 697)

(N = 465)

(Cases/controls)

OR (95 % CI)b

P b

OR (95 % CI)b

P b

OR (95 % CI)b

P b

KCTD10

rs1477117

521/156/16

326/123/10

0.136/0.156

0.70 (0.49–1.00)

0.048

1.13 (0.39–3.33)

0.820

0.79 (0.58–1.08)

0.135

rs11066782

517/160/15

311/135/11

0.137/0.172

0.62 (0.43–0.88)

0.007

1.02 (0.35–2.94)

0.975

0.71 (0.53–0.97)

0.029

rs11613718

494/160/15

308/139/9

0.142/0.172

0.63 (0.44–0.90)

0.010

1.12 (0.37–3.35)

0.840

0.73 (0.54–0.99)

0.044

rs11615336

502/166/16

317/120/10

0.145/0.157

0.74 (0.52–1.06)

0.104

1.12 (0.38–3.30)

0.835

0.83 (0.61–1.12)

0.223

MMAB

rs12817689

519/158/15

319/113/10

0.136/0.150

0.78 (0.54–1.12)

0.173

1.10 (0.38–3.21)

0.865

0.85 (0.62–1.16)

0.311

rs11067233

562/122/7

329/118/8

0.098/0.147

0.50 (0.34–0.73)

<0.001

0.73 (0.20–2.67)

0.631

0.57 (0.40–0.80)

0.001

  1. MAF minor allele frequency, OR odds ratio, CI confidence interval
  2. aMajor homozygote/heterozygote/rare homozygote
  3. bLogistic regression with adjustment for sex, age and smoking