Combined genotypesa
| Cases | Controls | OR (95 % CI)b
|
P
b
|
---|
0 | 383 | 222 | 1.00 | |
1–2 | 244 | 166 | 0.71 (0.50–0.99) | 0.045 |
3–4 | 33 | 55 | 0.33 (0.18–0.58) | <0.001 |
P for trend | | | | <0.001 |
0–2 | 627 | 388 | 1.00 | |
3–4 | 33 | 55 | 0.38 (0.21–0.66) | <0.001 |
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OR odds ratio, CI confidence interval
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aThe combined genotypes were according to favorable alleles carried (rs11066782-T, rs11613718-T and rs11067233-G were considered as favorable alleles)
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bLogistic regression with adjustment for sex, age and smoking