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Table 3 Univariate and multivariate analysis of association of APOE genotype with dyslipidemia and its componentsP-values obtained by univariate logistic regression

From: Association of apolipoprotein E polymorphism with plasma lipid disorders, independent of obesity-related traits in Vietnamese children

   OR (95 % CI) P-value OR* (95 % CI) P *-value
Hypoalphalipoproteinemia
APOE genotype ε3/ε3 1   1  
ε2 carrier 1.19 (0.43–3.26) 0.739 1.29 (0.45–3.63) 0.635
ε4 carrier 2.68 (1.17–6.14) 0.020 2.78 (1.18–6.58) 0.020
Hyperbetalipoproteinemia
APOE genotype ε3/ε3 1   1  
ε2 carrier 0.86 (0.29–2.56) 0.785 1.06 (0.33–3.35) 0.923
ε4 carrier 2.69 (1.22–5.94) 0.014 2.08 (0.85–5.10) 0.110
Hypertriglyceridemia
APOE genotype ε3/ε3 1   1  
ε2 carrier 1.12 (0.72–1.74) 0.617 1.16 (0.72–1.86) 0.538
ε4 carrier 1.15 (0.71–1.86) 0.575 1.04 (0.62–1.75) 0.869
Hypercholesterolemia
APOE genotype ε3/ε3 1   1  
ε2 carrier 0.64 (0.22–1.88) 0.421 0.76 (0.26–2.26) 0.624
ε4 carrier 1.82 (0.83–4.00) 0.138 1.62 (0.70–3.77) 0.259
rs429358 Dominant T/T 1   1  
Dyslipidemia
APOE genotype ε3/ε3 1   1  
ε2 carrier 1.06(0.70–1.60) 0.784 1.14 (0.73–1.77) 0.564
ε4 carrier 1.36 (0.89–2.08) 0.153 1.26 (0.80–1.99) 0.312
  1. P*-values obtained by multivariate logistic regression and adjusted for age, gender, BMI, residence and province
  2. Bold values indicate a statistically significant after adjustment for multiple testing (P-values < 0.025)