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Table 6 Correlations between protein expressions (MAPK-1,HIF-1αand HO-1) and coronary angiography indicators among groups of premenopausal and postmenopausal women

From: Associations of proteins relevant to MAPK signaling pathway (p38MAPK-1,HIF-1 and HO-1) with coronary lesion characteristics and prognosis of peri-menopausal women

Indicators

Premenopausal-CAD group

Postmenopausal-CAD group

MAPK-1

HIF-1α (ng/L)

HO-1 (ng/L)

MAPK-1

HIF-1α (ng/L)

HO-1 (ng/L)

Lesion vessels

 Left main coronary artery

4.4 ± 0.1

13.8 ± 4.3

230.5 ± 50.2

4.7 ± 0.2

15.8 ± 4.2

264.3 ± 89.8

 Anterior descending artery

4.5 ± 0.1

17.2 ± 7.3*

374.4 ± 195.3*

4.7 ± 0.12

21.4 ± 10.1*

397.7 ± 159.4*

 Circumflex coronary artery

4.5 ± 0.1

20.3 ± 11.3@

419.6 ± 210.1@

4.8 ± 0.1

29.9 ± 12.1@

482.8 ± 278.4@

 Right coronary artery

4.6 ± 0.2

24.1 ± 14.2&

527.1 ± 273.1&

4.8 ± 0.1

35.9 ± 15.0&

598.1 ± 262.1&

Number of stenosed coronary vessel

 Single vessel lesion

4.5 ± 0.2

16.0 ± 3.5

283.6 ± 82.0

4.7 ± 0.2

16.1 ± 3.7

278.4 ± 91.7

 Double vessel lesion

4.5 ± 0.1a

19.3 ± 9.9a

409.7 ± 175.3a

4.7 ± 0.1a

23.6 ± 10.1a

349.8 ± 183.2a

 Triple vessel lesion

4.5 ± 0.2b

29.1 ± 13.2b

561.6 ± 280.6b

4.8 ± 0.1b

39.6 ± 13.2b

637.9 ± 257.6b

Lesion type

 Type A

4.4 ± 0.2

14.7 ± 2.9

236.9 ± 90.2

4.7 ± 0.1

18.7 ± 4.5

293.5 ± 85.4

 Type B

4.5 ± 0.1c

17.6 ± 8.1c

418.7 ± 161.3c

4.7 ± 0.1c

25.1 ± 7.9c

375.8 ± 155.5c

 Type C

4.6 ± 0.2d

30.7 ± 11.4d

520.6 ± 224.5d

4.8 ± 0.2d

34.7 ± 10.8d

614.5 ± 249.5d

  1. *: compared with left main coronary artery; @: compared with anterior descending artery; &: compared with circumflex coronary artery; a: compared with single vessel lesion; b: compared with double vessel; c: compared with type A; d: compared with type B