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Table 4 Effect of treatment meal on participant postprandial serum endotoxin concentration over timea

From: Postprandial serum endotoxin in healthy humans is modulated by dietary fat in a randomized, controlled, cross-over study

Meal

Time postprandial (minutes)

0

60

120

180

240

300

Low Fat

0.39 ± 0.09

0.45 ± 0.14

0.37 ± 0.10

0.28 ± 0.03

0.25 ± 0.02

0.32 ± 0.07

Saturated

0.27 ± 0.03

0.39 ± 0.11

0.51 ± 0.14

0.49 ± 0.17

0.31 ± 0.08

0.38 ± 0.20

N-3

0.43 ± 0.15

0.29 ± 0.07

0.26 ± 0.03

0.24 ± 0.02

0.26 ± 0.02

0.26 ± 0.02

N-6

0.36 ± 0.12

0.59 ± 0.20

0.46 ± 0.16

0.36 ± 0.09

0.24 ± 0.02

0.31 ± 0.09

  1. a All values expressed as mean ± SEM. Measured endotoxin expressed as endotoxin units/mL; Participant serum (n = 20 samples/time-point) endotoxin was determined in duplicate using the kinetic chromogenic LAL endotoxin assay. Treatment effect was analyzed following the log-transformation of measured endotoxin values using repeated measures ANCOVA with baseline as a covariate as described in Methods. The n-3 fatty acid rich test meal effected a significantly lower (p < 0.05) postprandial serum endotoxin than the saturated fatty acid rich test meal
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Lipids in Health and Disease

ISSN: 1476-511X