A proteomic analysis of acute leukemia cells treated with 9-hydroxyoctadecadienoic acid

Table 1 The identification of protein spots on 2-DE

Spot	Accession	Protein name	Gene	M.W.	pI	Score
mRNA metabolic process
13	Q69YN4	Protein virilizer homolog↓	KIAA1429	202584.08	4.44	66.6
9	Q13185	Chromobox protein homolog 3↓	CBX3	20969.41	4.96	84.6
22	P61978	Heterogeneous nuclear ribonucleoprotein K↑	HNRNPK	48760.25	5.17	54.5
Protein binding
32	P60709	Actin, cytoplasmic 1 ↑	ACTB	42051.86	5.15	122
23	P05388	60S acidic ribosomal protein P0↑	RPLP0	34388.88	5.77	170
29	P11171	Protein 4.1↑	EPB41	81755.32	5.54	61
6	Q6PK50	HSP90AB1 protein↓	HSP90AB1	40270.42	4.61	78.6
DNA replication
1	Q01105	Protein SET↓	SET	30974.22	3.86	98
2	Q01105	Protein SET↓	SET	31310.48	3.83	202
5	P12004	Proliferating cell nuclear antigen↓	PCNA	29092.42	4.31	94.1
Cytoskeleton
21	P63261	Actin, cytoplasmic 2 ↑	ACTG1	42107.92	5.16	321
17	I3L1U9	Actin, cytoplasmic 2, N-terminally processed↑	ACTG1	23886.98	5.11	129
Apoptosis process
26	P51878	Caspase-5↑	CASP5	33966.33	8.55	60.4
Negative regulation of myeloid cell differentiation
4	E9PKG1	Protein arginine N-methyltransferase 1↓	PRMT1	38198.03	6.06	106
Unknown
8	P35527	Keratin, type I cytoskeletal 9↓	KRT9	62254.9	4.89	67.1
31	Q15195	Plasminogen-like protein A↑	PLGLA	11135.6	6.5	63.6
28	Q8IUZ0	Isoform 3 of Leucine-rich repeat-containing protein↑	LRRC49	74491.59	7.15	60
27	B4DVQ0	cDNA FLJ58286, highly similar to Actin, cytoplasmic 2↑		37666.76	5.45	147
20	B4E335	cDNA FLJ52842, highly similar to Actin, cytoplasmic 1↑		39542.66	5.28	207
19	B4DW52	cDNA FLJ55253, highly similar to Actin, cytoplasmic 1↑		38950.3	5	148

ISSN: 1476-511X