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Table 1 Clinical and biochemical characteristics of the patients included in this study

From: Positive association between serum apolipoprotein M levels and hepatitis B virus DNA load in HBeAg-negative chronic hepatitis B

 

Control

HBeAg-negative

HBeAg-positive

Subjects, n

79

73

50

Demographics

 Age, years

44 ± 12

44 ± 13

40 ± 12

 Sex, % male

87%

85%

86%

 Body mass index, kg/m2

22.2 ± 2.2

22.3 ± 2.1

22.1 ± 2.1

Lipids profile

 Triglycerides, mmol/L

1.1 ± 0.41

1.72 ± 0.50*

2.74 ± 0.62#&

 Total cholesterol, mmol/L

4.4 ± 0.57

3.35 ± 1.33*

4.12 ± 1.21&

 HDL-C, mmol/L

1.35 ± 0.21

0.67 ± 0.47*

0.60 ± 0.36#

 LDL-C, mmol/L

2.86 ± 0.53

1.96 ± 0.89*

2.59 ± 1.10&

 Apolipoprotein A, g/L

1.38 ± 0.19

0.67 ± 0.39*

0.62 ± 0.34#

 Apolipoprotein B, g/L

0.97 ± 0.16

0.99 ± 0.44

1.24 ± 0.34#&

 Apolipoprotein M, mg/L

13.95 ± 7.11

52.42 ± 28.09*

58.32 ± 27.06#

 Lipoprotein(a), g/L

102 ± 2.81

20.67 ± 3.21*

26.72 ± 3.73#

liver biochemical profile

 Alanine aminotransferase, IU/L

18.25 ± 1.56

99.73 ± 4.50*

216.77 ± 4.17#&

 Aspartate transaminase, IU/L

20.11 ± 1.25

99.74 ± 2.95*

171.25 ± 2.80#&

 Log HBV DNA

 

4.32 ± 2.03

5.61 ± 1.97&

  1. Data are presented as means ± standard deviations. Values for triglyceride, lipoprotein a, ALT, and AST levels were converted into a logarithmic form prior to analysis. *p < 0.05, HBeAg-negative chronic hepatitis B (CHB) compared to the control. # p < 0.05, HBeAg-positive CHB compared to the control. &p < 0.05, HBeAg-positive CHB compared to HBeAg-negative CHB
  2. HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, IU international units