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Fig. 1 | Lipids in Health and Disease

Fig. 1

From: Myeloperoxidase-oxidized high density lipoprotein impairs atherosclerotic plaque stability by inhibiting smooth muscle cell migration

Fig. 1

Mass Spectrometry analysis of HDL and MPO oxidized HDL. a Results from the selected ion monitoring (SIM) analysis of the native HDL, Cl-HDL and NO2-HDL samples. The data were obtained by normalizing the peak areas for the W72 containing peptides (LLDNWDSVTSTFSK) by the peak areas of the reference peptides. The reference peptides utilized in these experiments are the unmodified apoA-I peptides ATEHLSTLSEK and QGLLPVLESFK. b Oxidized W72 of the native HDL, Cl-HDL and NO2-HDL samples was also analyzed, with singly oxidized product, W + O (16 Da), doubly oxidized product, W + 2O (32 Da), and the oxidation of W to kynurenine (W + 4 Da) (**p < 0.01 compared with HDL group)

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Lipids in Health and Disease

ISSN: 1476-511X