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Fig. 6 | Lipids in Health and Disease

Fig. 6

From: Myeloperoxidase-oxidized high density lipoprotein impairs atherosclerotic plaque stability by inhibiting smooth muscle cell migration

Fig. 6

Native and oxHDL’s effects on SMC migration are dependent on SR-BI. a Representative agarose gel of SR-BI genotype assay by PCR. Wild type (WT) mice were identified by a band at 630 bp, while SR-BI (−/−) mice were identified by band at 330 bp. b Western blot analysis of SMCs from wild type (WT) and SR-BI (−/−) mice. c In vitro transwell assay was performed to analyze aortic SMC migration in SR-BI (−/−) mice. The native and oxHDL was applied to SMC at a concentration of 100 μg /ml for 12 h. The cells were stained and photographed. d Migrating cells were counted and compared (no significant difference was observed between the four groups)

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