Increase of cytosolic phospholipase A2 as hydrolytic enzyme of phospholipids and autism cognitive, social and sensory dysfunction severity

Table 2 ROC curves of PE (mmole/l), PS (mmole/l), PC (mmole/l), cPLA2 (ng/ml) in autistic groups

Parameters		Patients with autism	CARS		SRS		SSP
Parameters		Patients with autism	Mild to moderate	Severe	Mild to moderate	Severe	Mild to moderate	Severe
PE (mmole/l)	AUC	0.985	0.971	1.000	1.000	0.985	1.000	1.000
	Best cutoff value	0.043	0.043	0.042	0.043	0.039	0.041	0.043
	Sensitivity%	97.5	95	100	92.9	100	100	100
	Specificity%	100	100	100	100	100	100	100
PS (mmole/l)	AUC	0.997	1.000	0.994	1.000	0.991	0.994	1.000
	Best cutoff value	0.061	0.061	0.059	0.059	0.061	0.059	0.061
	Sensitivity%	97.5	100.0	95.0	100.0	92.9	95.2	100.0
	Specificity%	100.0	100.0	100.0	100.0	100.0	100.0	100.0
PC (mmole/l)	AUC	0.996	0.995	0.996	0.996	0.995	0.996	0.993
	Best cutoff value	1.447	1.447	1.422	1.447	1.419	1.422	1.447
	Sensitivity%	100.0	100.0	100.0	100.0	100.0	100.0	100.0
	Specificity%	97.4	97.4	97.4	97.4	97.4	97.4	97.4
cPLA2 (ng/ml)	AUC	1.000	1.000	1.000	1.000	1.000	1.000	1.000
	Best cutoff value	1.114	1.114	1.332	1.114	1.149	1.149	1.114
	Sensitivity%	100.0	100.0	100.0	100.0	100.0	100.0	100.0
	Specificity%	100.0	100.0	100.0	100.0	100.0	100.0	100.0

Demonstrates the ROC analysis data as AUC, cutoff values, specificity, and sensitivity of the measured parameters. All parameters exhibited AUC values close to 1 and satisfactory values of accuracy presented as high specificity and sensitivity

ISSN: 1476-511X