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Table 2 Comparison of demographic, lifestyle characteristics, serum lipid profiles and the genotype and allele frequencies of the SPTLC3 rs364585 SNP between males and females in the Han and Jing populations

From: Association of the SPTLC3 rs364585 polymorphism and serum lipid profiles in two Chinese ethnic groups

Parameter Han t (x 2) P Jing t (x 2) P
Male Female Male Female
No. of patients 405 419    389 394   
Age (years) 56.88 ± 11.64 57.65 ± 13.10 −0.888 0.375 57.77 ± 14.20 56.64 ± 12.27 1.129 0.234
Height (cm) 162.99 ± 5.56 151.76 ± 6.51 26.538 0.000 162.94 ± 6.60 153.29 ± 5.82c 21.728 0.000
Weight (kg) 60.29 ± 8.53 52.54 ± 8.83 12.820 0.000 62.35 ± 10.02b 55.30 ± 8.87c 10.437 0.000
Body mass index (kg/m2) 22.68 ± 2.81 22.80 ± 3.52 −0.560 0.567 23.42 ± 3.10c 23.50 ± 3.30b −0.333 0.740
Waist circumference (cm) 78.31 ± 8.19 76.63 ± 9.49 2.730 0.006 81.59 ± 9.83c 79.19 ± 8.40c 3.677 0.000
Smoking status (n%)
 Non-smoker 248 (61.2) 418 (99.8)    264 (67.9) 392 (99.5)   
 Smoker 157 (38.8) 1(0.2) 196.00 0.000 115 (32.1)a 2 (0.5) 133.70 0.000
Alcohol consumption (n%)
 Non- drinker 232 (57.3) 416 (99.3)    292(75.1) 389 (98.7)   
 Drinker 173 (42.7) 3 (0.7) 216.01 0.000 97(24.9)c 5 (1.3) 96.65 0.000
Systolic blood pressure (mmHg) 130.14 ± 16.58 134.58 ± 20.79 −3.392 0.001 132.26 ± 20.77 132.11 ± 23.00 0.096 0.924
Diastolic blood pressure (mmHg) 81.99 ± 10.38 81.58 ± 10.50 0.554 0.580 80.68 ± 10.61 80.02 ± 10.00a 0.901 0.368
Pulse pressure (mmHg) 48.16 ± 13.21 53.00 ± 16.44 −4.651 0.000 51.59 ± 16.87b 52.09 ± 18.71 −0.403 0.687
Glucose (mmol/l) 6.58 ± 1.08 6.68 ± 1.04 −1.348 0.178 6.94 ± 1.75c 6.79 ± 1.49 1.307 0.191
Total cholesterol (mmol/l) 4.90 ± 0.83 5.06 ± 0.87 −2.734 0.006 5.04 ± 0.82a 5.11 ± 0.97 −1.165 0.244
Triglyceride (mmol/l) 1.39(1.71) 1.40(1.63) −2.720 0.007 1.48(1.83) 1.40(1.63) −0.963 0.336
HDL-C (mmol/l) 1.74 ± 0.55 1.87 ± 0.48 −2.417 0.000 1.75 ± 0.46 1.83 ± 0.45 −2.417 0.016
LDL-C (mmol/l) 2.86 ± 0.43 2.89 ± 0.45 −3.615 0.382 2.82 ± 0.37 2.81 ± 0.48a 0.183 0.855
Apo A1 (g/l) 1.33 ± 0.21 1.32 ± 0.20 0.263 0.793 1.26 ± 0.21c 1.30 ± 0.23 −2.764 0.006
ApoB (g/l) 1.06 ± 0.23 1.05 ± 0.26 0.465 0.642 1.04 ± 0.22 1.03 ± 0.24 1.011 0.312
ApoA1/ApoB 1.31 ± 0.36 1.33 ± 0.37 −0.697 0.486 1.26 ± 0.40 1.32 ± 0.37 −2.102 0.036
Genotype [n(%)]
 GG 105(25.9) 118(28.2)    108(27.8) 127(32.2)   
 GA 188(46.4) 204(48.7)    188(48.3) 183(46.4)   
 AA 112(27.7) 97(23.2) 2.250 0.325 93(23.9) 84(21.3) 2.029 0.363
Allele [n(%)]
 G 398(49.1) 440(52.6)    404(51.9) 437(55.5)   
 A 412(50.9) 398(47.4) 1.972 0.171 374(48.1) 351(44.5) 1.961 0.161
  1. HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, Apo Apolipoprotein. The value of triglyceride was presented as median (interquartile range), the difference between the two groups was determined by the Wilcoxon-Mann-Whitney test. a P < 0.001, b P < 0.01 and c P < 0.05 in comparison with the same sex subgroup of the Han ethnic group