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Table 4 Comparison between the SPTLC3 rs364585 SNP genotypes and serum lipid levels between males and females in the Han and Jing populations

From: Association of the SPTLC3 rs364585 polymorphism and serum lipid profiles in two Chinese ethnic groups

Ethnic/ Genotype

n

TC

(mmol/L)

TG

(mmol/L)

HDL-C

(mmol/L)

LDL-C

(mmol/L)

ApoA1

(g/L)

ApoB

(g/L)

ApoA1

/ApoB

Han/male

 GG

105

4.85 ± 0.88

1.32(0.62)

1.80 ± 0.45

2.75 ± 0.41

1.34 ± 0.22

1.03 ± 0.21

1.35 ± 0.38

 GA / AA

300

4.92 ± 0.80

1.41(0.72)

1.72 ± 0.57

2.90 ± 0.42

1.32 ± 0.20

1.07 ± 0.23

1.30 ± 0.35

  F

 

1.560

1.674

2.028

11.855

1.117

2.088

2.563

  P

 

0.212

0.094

0.155

0.001

0.291

0.149

0.110

Han/female

 GG

118

5.07 ± 0.90

1.41(0.68)

1.87 ± 0.46

2.83 ± 0.47

1.32 ± 0.18

1.05 ± 0.29

1.34 ± 0.40

 GA / AA

301

5.05 ± 0.86

1.40(0.60)

1.87 ± 0.48

2.93 ± 0.44

1.32 ± 0.20

1.05 ± 0.25

1.33 ± 0.36

  F

 

0.004

0.358

0.509

2.434

0.128

0.004

1.096

  P

 

0.951

0.720

0.476

0.120

0.721

0.948

0.296

Jing/male

 GG

108

4.86 ± 0.72

1.40(0.95)

1.81 ± 0.42

2.75 ± 0.36

1.29 ± 0.23

1.06 ± 0.23

1.31 ± 0.48

 GA/ AA

281

5.12 ± 0.85

1.50(0.81)

1.73 ± 0.48

2.85 ± 0.38

1.25 ± 0.20

1.05 ± 0.21

1.25 ± 0.37

  F

 

14.266

0.448

0.278

6.305

1.200

0.616

0.465

  P

 

0.000

0.654

0.598

0.012

0.274

0.433

0.496

Jing/female

 GG

127

5.11 ± 0.98

1.40(0.59)

1.92 ± 0.42

2.72 ± 0.53

1.31 ± 0.21

1.02 ± 0.27

1.36 ± 0.44

 GA/ AA

267

5.12 ± 0.97

1.39(0.66)

1.79 ± 0.45

2.86 ± 0.48

1.30 ± 0.25

1.04 ± 0.23

1.31 ± 0.33

  F

 

0.035

0.669

7.450

6.235

0.018

0.005

1.308

  P

 

0.852

0.503

0.007

0.013

0.892

0.945

0.253

  1. TC total cholesterol, TG triglyceride, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, ApoA1 apolipoprotein A1, ApoB apolipoprotein B, ApoA1/ApoB the ratio of apolipoprotein A1 to apolipoprotein B. The values of triglyceride were presented as median (interquartile range), and the difference between the GG and GA/AA genotypes was determined by the Wilcoxon-Mann-Whitney test