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Table 4 Comparison between the SPTLC3 rs364585 SNP genotypes and serum lipid levels between males and females in the Han and Jing populations

From: Association of the SPTLC3 rs364585 polymorphism and serum lipid profiles in two Chinese ethnic groups

Ethnic/ Genotype n TC
(mmol/L)
TG
(mmol/L)
HDL-C
(mmol/L)
LDL-C
(mmol/L)
ApoA1
(g/L)
ApoB
(g/L)
ApoA1
/ApoB
Han/male
 GG 105 4.85 ± 0.88 1.32(0.62) 1.80 ± 0.45 2.75 ± 0.41 1.34 ± 0.22 1.03 ± 0.21 1.35 ± 0.38
 GA / AA 300 4.92 ± 0.80 1.41(0.72) 1.72 ± 0.57 2.90 ± 0.42 1.32 ± 0.20 1.07 ± 0.23 1.30 ± 0.35
F   1.560 1.674 2.028 11.855 1.117 2.088 2.563
P   0.212 0.094 0.155 0.001 0.291 0.149 0.110
Han/female
 GG 118 5.07 ± 0.90 1.41(0.68) 1.87 ± 0.46 2.83 ± 0.47 1.32 ± 0.18 1.05 ± 0.29 1.34 ± 0.40
 GA / AA 301 5.05 ± 0.86 1.40(0.60) 1.87 ± 0.48 2.93 ± 0.44 1.32 ± 0.20 1.05 ± 0.25 1.33 ± 0.36
F   0.004 0.358 0.509 2.434 0.128 0.004 1.096
P   0.951 0.720 0.476 0.120 0.721 0.948 0.296
Jing/male
 GG 108 4.86 ± 0.72 1.40(0.95) 1.81 ± 0.42 2.75 ± 0.36 1.29 ± 0.23 1.06 ± 0.23 1.31 ± 0.48
 GA/ AA 281 5.12 ± 0.85 1.50(0.81) 1.73 ± 0.48 2.85 ± 0.38 1.25 ± 0.20 1.05 ± 0.21 1.25 ± 0.37
F   14.266 0.448 0.278 6.305 1.200 0.616 0.465
P   0.000 0.654 0.598 0.012 0.274 0.433 0.496
Jing/female
 GG 127 5.11 ± 0.98 1.40(0.59) 1.92 ± 0.42 2.72 ± 0.53 1.31 ± 0.21 1.02 ± 0.27 1.36 ± 0.44
 GA/ AA 267 5.12 ± 0.97 1.39(0.66) 1.79 ± 0.45 2.86 ± 0.48 1.30 ± 0.25 1.04 ± 0.23 1.31 ± 0.33
F   0.035 0.669 7.450 6.235 0.018 0.005 1.308
P   0.852 0.503 0.007 0.013 0.892 0.945 0.253
  1. TC total cholesterol, TG triglyceride, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, ApoA1 apolipoprotein A1, ApoB apolipoprotein B, ApoA1/ApoB the ratio of apolipoprotein A1 to apolipoprotein B. The values of triglyceride were presented as median (interquartile range), and the difference between the GG and GA/AA genotypes was determined by the Wilcoxon-Mann-Whitney test